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“The more obese people are, the less effective vitamin D intake” : Donga Science

Harvard Medical School-affiliated Brigham and Women’s Hospital research team

Courtesy of Getty Images Bank

There is something that is not missing from the holiday gift preference survey. it’s just nutrients. In particular, vitamin D is essential for height growth in children and teenagers and is also related to immunity, so it is also popular among the elderly, including the middle-aged.

Vitamin D is an essential nutrient involved in a variety of biological processes. It helps our body absorb minerals like calcium and magnesium. It is also known to help prevent cancer or cardiovascular disease by inducing the production of immune substances.

Most Koreans lack vitamin D, so a high dose of vitamin D is supplemented, but a study has found that the more obese people are, the less effective vitamin D intake is.

A research team led by Deirdre Tobias, a researcher at Brigham and Women’s Hospital affiliated with Harvard Medical School, published a study on the international journal ‘Jama Network Open’ on the 17th (local time) that the higher the body mass index (BMI), the lower the rate of vitamin D metabolism. .

BMI is a number obtained by dividing body weight (kg) by the square of height (m). This condition is classified as extremely obese.

The research team followed the blood data of 2,742 people who started taking vitamin D for two years and measured biomarkers such as calcium, a metabolite of vitamin D, and levels of parathyroid hormone, which helps the body use vitamin D.

As a result of the study, calcium and parathyroid hormone levels increased in people with a BMI of less than 25, but there was no significant effect of vitamin D supplementation in those with a higher BMI. The research team analyzed that the fat-soluble vitamin, vitamin D, is sequestered in adipose tissue and not sufficiently absorbed into the body.

In addition, in the case of patients who underwent gastric resection surgery for obesity treatment, it was confirmed that the blood vitamin D level increased significantly even though they did not take vitamin D supplements separately while losing weight extremely. As part of the fat tissue in the body disappeared, the level of vitamin D in the blood naturally rose.

Researcher Tobias said, “We confirmed that the higher the BMI, the lower the effect of vitamin D supplementation.” “The concentration of vitamin D required to prevent cancer and diabetes may be higher in obese patients.

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