In recent years, research into treatments for Parkinson’s disease has made significant progress. Recently, a new research breakthrough promises to provide remarkable results in long-term treatment without generating side effects.
The research, led by Aarhus University and published in the journal Nature Communications on Tuesday, has developed an innovative method that ensures a much higher purity of dopaminergic cells, essential in treating Parkinson’s disease.
Professor Mark Denham, group leader at the Danish Translational Neuroscience Research Institute (DANDRITE), explains that achieving high purity is essential for restoring movement in Parkinson’s patients.
This method allowed stem cells to be genetically modified in the laboratory, preventing the generation of the incorrect types of nerve cells. Thus, the genetically modified stem cells showed an increased capacity to produce specific nerve cells needed for the treatment of Parkinson’s disease, known as dopaminergic cells.
Studies have also shown that genetically modified stem cells have helped restore movements in animal models of Parkinson’s.
This discovery opens new and promising perspectives in the therapeutic approach to Parkinson’s disease. Experiments in mice emphasized the importance of both the quantity and purity of the cultured stem cells for the efficacy and durability of the treatment.
Using these genetically modified cells, the team was able to achieve a higher purity of dopaminergic cells, thereby reducing recovery time and the risk of relapse, lessening the need for drugs.
Marks emphasized that the goal is to help patients become drug dependent, which requires a high purity of the cells.
The team plans to start proceedings for a clinical trial to test this new approach in treating patients diagnosed with Parkinson’s.
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2023-12-07 20:31:41
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