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The duration of immunity in patients with COVID is named

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Antibodies to coronavirus can last up to 15 months

After infection, antibodies decreased slowly in the first six months and then remained stable for up to 15 months.

Scientists from Sweden and Italy have found that the majority of COVID-19 patients retain their immunity for up to 15 months. It is reported by News Medical with a link to an article that was published on the bioRxiv.org preprint site.

The authors collected 188 blood tests from 136 patients with coronavirus, in whom the disease was accompanied by characteristic symptoms and proceeded in various forms, from mild to severe.

Plasma from 108 people with a confirmed negative PCR test was used as a control sample.

The results showed that in the first six months, the titers of specific IgG antibodies in 94% of patients reached a maximum 15-28 days after the onset of symptoms, gradually decreased by about four times by the end of the sixth month, and then remained stable until 15 months.

The high level of antibodies remained for longer in those who had been ill with COVID-19 in a severe form.

For comparison, the scientists assessed the level of specific IgG antibodies in the plasma of the vaccinated. It turned out that 14-35 days after the introduction of the first dose of the vaccine, the antibody titers were similar to those in those who had recovered six months after infection.

After the second dose, they corresponded to the maximum natural response rate in recovering patients.

In addition to the main strain SARS-CoV-2, the authors tested the effectiveness of antibodies against beta, gamma and delta variants for up to 15 months after infection.

It was confirmed that the neutralizing activity of antibodies, albeit to a lesser extent, is preserved for these variants of the coronavirus.

It is emphasized that the time during which the study was carried out is not enough to assess long-term immunity, but it is obvious that in most patients who have undergone coronavirus, it persists up to 15 months after infection.


bioRxiv publishes preliminary scientific reports that are not peer-reviewed and therefore should not be regarded as definitive, as guidelines for clinical practice, or as established information.


Previously, Italian scientists found that antibody levels remain high nine months after being infected with the coronavirus, despite the severity of the disease.

Scientists have found out why the vaccine is not always effective

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