Post-mortem brain studies of people who suffer from Parkinson’s disease have shown that brain cells that control motor activity are “clogged” with accumulations of alpha synuclein.
According to ToDay News Ufa with reference to Nature Neuroscience, when working with mice, researchers were able to sow alpha synuclein in intestinal neurons. As a result, it was found that the substance can spread upwards and act on brain neurons. This process depends on age.
Injection into mice that carry genes helps to reduce protein accumulation and partially restore the proper functioning of the intestines.
Aggregation begins in the intestines. Substances then enter the brain through the vagus nerve. Scientists even introduced the necessary aggregates into the digestive tract of mice. As it turned out, in adult mice clusters progress, but motor disorders do not occur. In elderly mice, the progression of clusters led to gastrointestinal disorders.
It was previously reported that a neuroscientist warned against trying to sleep less than 8 hours a day.
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