Ciesek in the Corona podcast: “Willingness to be vaccinated will increase” | NDR.de – news

The Standing Vaccination Commission updated its recommendations on Covid-19 vaccination on January 8, 2021.
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Allergic reactions extremely rare and easily treatable

The CDC, for example, has a first Study of allergic reactions to the vaccine by Biontech / Pfizer released. Data was collected from 1.89 million vaccinations in which 175 allergic incidents were reported. Of these, in turn, 21 proved to be a real anaphylactic reaction (e.g. shortness of breath, drop in blood pressure, nettle reaction). In 17 of these cases there was also an allergic history, seven patients were severely allergic. Ciesek’s conclusion: allergic reactions occur extremely rarely and almost always in people with a corresponding history. They are easily treatable and not specific for an mRNA vaccine. They could occur with every drug administration. The CDC study also does not indicate long-term damage, on average the allergic reaction occurred within 13 minutes after the vaccination, i.e. in a period in which the vaccinated are still medically observed anyway.

Vaccination strategy: use the scope for a second dose

With regard to the vaccination strategy in Germany, Ciesek argues that the leeway that is covered by the approval should be exploited. The necessary second dose should only be administered after four to six weeks instead of the previous 21 days. Unlike in Great Britain, the vaccination centers in Germany and many other countries withheld the second dose for those who had already been vaccinated. If the available vaccine were to be vaccinated completely in initial doses, this would have the advantage, according to Ciesek, that more cases could be prevented and the pandemic could be positively influenced. However, it must be ensured that the people get the second dose within six weeks, otherwise one would only get a partial immune response (protective effect of the Biontech vaccine after the first dose: 52.4 percent, after the second dose: 94.8 percent).

Hope for a longer immune response after vaccinations

Ciesek expects the situation to ease when more vaccines are added. Astrazeneca’s serum is expected to be approved by the end of January. The first and second dose, however, would have to come from the same vaccine: “You continue to vaccinate with the vaccine you started with.” Ciesek emphasized again that despite the vaccination, the anti-corona measures must continue to be observed. According to Ciesek, a study published in the USA in the specialist journal “Science” that looks at different areas of the immune system after having been infected gives hope for a longer immune response after vaccinations. However, there was still a lack of reliable data.

New virus variant from Japan and Brazil

When it comes to the effectiveness of the vaccine against mutations, science also has “first data that give the all-clear,” said Ciesek. Biontech was able to show in the laboratory that the vaccine prevents cells from being infected by virus particles with the N501Y mutation. This mutation carries both the English and the South African variant, which has just been detected for the first time in Germany. However, according to Ciesek, it is important “to look at the interplay of mutations. They can have a different biological effect than individual mutations.” For example, there was still no virological data on a new virus variant detected in Brazil and Japan that also carries the well-known N501Y mutation. As things stand, there is no reason for greater concern, says Ciesek: “As long as the vaccines are effective, I am relatively relaxed.”

Further information

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What is an aerosol? What is a cell culture? Our glossary explains the most important technical terms from our podcast with virologists Christian Drosten and Sandra Ciesek. more

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Coronavirus update: Podcast with Christian Drosten and Sandra Ciesek

The coronavirus pandemic has led to some drastic restrictions on public life in Germany and around the world. The more the virus spread, the more people wanted to know about it. NDR Info responded to this need for information with the coronavirus podcast. Every Tuesday, Christian Drosten, head of virology at the Berlin Charité, and Sandra Ciesek, director of the Institute for Medical Virology at the University Hospital Frankfurt am Main, answer current questions on a weekly basis.

Further information

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Here you will find all episodes broadcast so far for reading and listening to as well as a scientific glossary and much more. more

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The virologist Christian Drosten provides expert knowledge in the podcast Coronavirus Update – together with virologist Sandra Ciesek. Here is an overview of all the episodes. more

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A third corona vaccine could still be approved in the EU in January. The pharmaceutical company AstraZeneca and the University of Oxford have applied for approval for their product. more

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Willingness to vaccinate – this will be particularly important in the future. Opinions are also formed on social media. However, with all sorts of fake news. more

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This means that the number of reported cases in the state remains high. There were 48 other deaths. More corona news in the live ticker. more

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This topic in the program:

NDR Info | The coronavirus update from NDR Info | 01/12/2021 | 17:00 o’clock

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