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Beware of Immune Dysfunction aka Immunosenescence in the Elderly During Covid-19 Vaccination, These Are the Causes!

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Being the most vulnerable group during the Covid-19 pandemic, the elderly are also vigilant about experiencing immune dysfunction during vaccination.

Report from Grid.ID Journalist, Devi Agustiana

Grid.ID – Vaccination program Covid-19 for categories the elderly The government has started over 60 years since 8 February 2021, and can be done in health facilities such as health centers or hospitals.

Vaccination for the elderly This is a follow-up to the issuance of an Emergency Use Authorization (EUA) from the Food and Drug Supervisory Agency (BPOM) for vaccine the.

However, because of the high number of deaths due to this Covid-19 for the elderly, various questions will appear, especially about vaccine this.

Also Read: How to Minimize Side Effects After Covid-19 Vaccination for the Elderly? Following are the advice from an internal medicine doctor

Among them are immunosenescence or immune dysfunction in the elderly.

Therefore, it is important to prepare the elderly so that vaccinations work optimally.

“The thing that needs to be considered regarding vaccination in the elderly is the occurrence immunosenescence or immune dysfunction due to age. This is related to the less than optimal response to vaccines, “said Prof. DR. dr. Siti Setiati, SpPD-KGer, M-Epid, FINASIM, Internal Medicine Sub-specialist Geriatric FKUI RSCM, Chair of the Medical Gerontology Association (PERGEMI).

Also Read: Experts Suggest Drinking Green Tea After Covid-19 Vaccination, Check Out the Reasons!

“Because immunosenescence“There is usually a low level of chronic inflammation due to a combination of decreased immunity, continuous exposure to antigens, and increased production of proinflammatory cytokines from senescent T cells and macrophages,” said Prof. Siti in the Entrasol Peel Tuntas virtual event Vaccine COVID-19 & Nutrition for Elderly which Grid.ID participated in, Sunday (7/3/2021).


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