Some biomarkers have been identified in spermatozoa that may indicate a propensity to father children with autism spectrum disorder. They are called “epigenetic” because they involve changes to molecular factors which regulate the activity of the genome, and can be passed on to future generations.
To say it is a study conducted among others byIvi-Rma of Valencia and the University of Washington which was published in the scientific journal Clinical Epigenetics. According to the researchers, these values can determine, with 90% accuracy, the future ailment.
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“We can potentially use it to assess whether a man will pass autism on to his children,” she said Michael Skinner, a professor of biological sciences at Washington State University and one of the authors of the study.
“It is also an important step towards identifying which factors could promote autism,” he adds.
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In the analysis they were 26 men involved, thirteen with autistic children and the same number without the disorder. The researchers looked at the DNA methylation, a chemical modification that occurs when a methyl group attaches itself to a DNA strand and can turn genes on or off. Researchers have identified 805 different regions of DNA methylation which can potentially act as an epigenetic biomarker for susceptibility to parent offspring with autism.
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