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WHO Recommendations for Flu Vaccines in 2023-2024 Northern Hemisphere Season

September 21, 2023

The World Health Organization (WHO) has announced recommendations on the viral composition of flu vaccines for the 2023-2024 flu season in the northern hemisphere.

WHO organizes these consultations twice a year with an advisory group of experts from the WHO Collaborating Centers and Essential Regulatory Laboratories to analyze data obtained from the surveillance of influenza viruses obtained by the Global Surveillance and Response System. WHO Influenza. National vaccine regulatory agencies and pharmaceutical companies use these recommendations to develop, manufacture and license influenza vaccines for the upcoming influenza season.

The viruses contained in influenza vaccines need to be periodically redefined to ensure their effectiveness, as influenza viruses, including those that circulate among and infect humans, are constantly evolving.

The WHO recommends the following composition for quadrivalent vaccines to be used in the 2023-2024 flu season in the northern hemisphere:

Those produced from embryonated eggs:

a strain analogous to A/Victoria/4897/2022 (H1N1)pdm09, a strain analogous to A/Darwin/9/2021 (H3N2), a strain analogous to B/Austria/1359417/2021 (B/Victoria lineage) and a strain analogous to B/Phuket/3073/2013 (B/Yamagata lineage).

Recombinants or those produced from cell cultures:

a strain analogous to A/Wisconsin/67/2022 (H1N1)pdm09m, a strain analogous to A/Darwin/6/2021 (H3N2), a strain analogous to B/Austria/1359417/2021 (B/Victoria lineage) and a strain analogous to B/Phuket/3073/2013 (B/Yamagata lineage)

The WHO recommends the following composition for trivalent vaccines to be used in the 2023-2024 flu season in the northern hemisphere:

Those produced from embryonated eggs:

a strain analogous to A/Victoria/4897/2022 (H1N1)pdm09, a strain analogous to A/Darwin/9/2021 (H3N2) and a strain analogous to B/Austria/1359417/2021 (B/Victoria lineage)

Recombinants or those produced from cell cultures:

a strain analogous to A/Wisconsin/67/2022 (H1N1)pdm09, a strain analogous to A/Darwin/6/2021 (H3N2) and a strain analogous to B/Austria/1359417/2021 (B/Victoria lineage)

2023-09-21 11:31:36
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