Himedik.com – UK study finds people who get injections Covid-19 vaccine of 2 different types experienced side effects most widely.
Fever was the most commonly reported side effect after people received two different doses of the Covid-19 vaccine or a combination.
A study found that a combination of the Covid-19 vaccine from Pfizer and AstraZeneca could cause more side effects than two doses of the same Covid-19 vaccine.
Because, giving one dose of each combined Covid-19 vaccine has a risk of causing mild to severe symptoms.
The Oxford-led Com-Cov study involved 830 participants aged 50 years and over and explored the efficacy of a combination of 2 Covid-19 vaccines. Overall, the Covid-19 vaccine combination triggered more side effects, including fever.
Other symptoms of the combined side effects of the two Covid-19 vaccines include:
- Chills
- Fatigue
- Headache
- Joint pain
- Bad taste
- Muscleache
“All of these side effects are more or less the same as the side effects of two doses of the same Covid-19 vaccine. However, these symptoms occur more frequently when people get a combination shot of the two Covid-19 vaccines,” said Matthew Snape, chief investigator and lead author of the study. professor of pediatrics and vaccinology at the University of Oxford quoted from Express.
According to Matthew, right now the best option is to inject two doses of the Covid-19 vaccine of the same type into people. Because, the results of clinical trials of each Covid-19 vaccine have also proven their efficacy.
Meanwhile, the study also found that the order in which two different doses of the Covid-19 vaccine were administered had an impact on the human immune response.
Inject AstraZeneca vaccine for the first dose and followed Pfizer vaccine for the second dose showed a better immune response.
However, the researchers found these results when two different doses of the Covid-19 vaccine were given at 4-week intervals.
This means that the combination of the Covid-19 vaccine can provide an immune response above the threshold when given at 4-week intervals.
“Young age groups may experience more side effects if they receive a combination of the two Covid-19 vaccines. These reactions are often associated with stimulation of the innate immune response, so a fundamental part of the immune response is sending inflammatory signals,” Matthew explained.
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