Müftüoğlu: Developments about the Russian vaccine proved me wrong

Hürriyet writer Prof. Dr. Osman Müftüoğlu wrote about the reliability and effectiveness of the Russian vaccine Sputnik V: The developments proved me wrong.

Health Minister Fahrettin Koca announced that a 50 million-dose contract was signed for the Sputnik V vaccine, which the Turkish Medicines and Medical Devices Agency approved for emergency use as a result of the examination and evaluation, and the first batch of vaccines will come this month.

Prof. Dr. Muftuoglu in today’s corner Recalling the article in October 2020 “Russians ‘We also found the vaccine‘when they made the statement, he did not believe that news, even ‘I will not have this vaccine until the information is clear’ I also expressed an opinion in the form of “ used the expressions.

Stating that the subsequent developments proved him wrong, Müftüoğlu continued his article as follows: “The data confirming the efficacy and safety of this new vaccine developed by the Gamaleya Institute in Russia were recently published in the famous medical journal The Lancet. So what is in that information? The 2 basic genes of the carrier adenoviruses used to produce Sputnik V, ‘E1 and E3 genes’ It is neutralized and cleaned with special methods. This cleaning work, especially the issue of clearing the E1 gene, is a very, very important detail. Because the E1 gene is a gene that controls the replication of the virus. If you cannot completely erase that gene and eliminate it, the adenovirus that enters your body with the vaccine can also have the opportunity to multiply.

If the E1 gene can be deleted completely, the carrier adenovirus will never be able to reproduce in the body, only ‘carrier post / vector’ can fulfill. As for the E3 gene… It is also an important point to delete the E3 gene. When you destroy this gene, it becomes easier for the carrier vector adenovirus to communicate with your immune system, thus maximizing the effectiveness of the vaccine. “

Referring to the side effects of the vaccine, Müftüoğlu claims that the company does not have any serious side effects other than fatigue, headache, flu, flu-like symptoms, skin irritation and pain at the vaccine site, but the European vaccine authority EMA or the US vaccine authority FDA has yet to say that these data are sufficient. He stated that he did not approve.

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