A person receives a vaccine against covid.
Between the side effects related to the Covid-19 vaccinecases of myocarditis and pericarditis are among those that have most concerned the population. However, it has been proven that its incidence varies depending on the age and sex of the individual receiving the injection, as well as the period in which it is administered. According to a recent study published in medRxivspace the second dose of the vaccine with respect to the first one minimum of 56 days would serve to reduce this adverse reaction.
After analyzing data from 46 studies, the authors of this research conclude that the incidence of myocarditis after the mRNA vaccines (Pfizer and Moderna) may be less if the dosing interval is increased if it is increased to eight weeks (56 days) between males between 18 and 29 years old which is precisely the one with the highest incidence. However, they warn that this decrease is more noticeable when the Pfizer compound is inoculated.
For this group, the same source points out, the notifications for myocarditis can exceed 100 cases per million. A figure far removed from the impact of this reaction among women of the same age, where its impact may be less than 20 cases per million.
It should be remembered that the indications for the administration of the second dose they change according to the type of whey in Spain and the rest of the Member States in the European Union. So the period of time that must pass between the first and the second puncture for the person to develop defenses that protect against the most serious forms of the disease is 21 days for the Pfizer vaccine and of 28 days in the case of Moderna.
On the other hand, the incidence of myocarditis or pericarditis after the second dose In person over 40 years old may also be higher when given in a period less than 31 days. Although in this case, the decline is compounded for Moderna compared to Pfizer.
Cases of myocarditis and pericarditis in Spain
As for the cases of myocarditis and pericarditis between the pediatric populationit is determined that “rarely” children under 11 years of age present these pathologies. Meanwhile, most cases of myocarditis involved men ages 20 to 30 (over 90 percent) with onset of symptoms two to four days after the second dose. And, within this group, a higher percentage of 84 percent was hospitalized for a short period of 2-4 days.
In Spain, a total of 321 notifications of myocarditis and pericarditis related to the 60.5 million doses of covid mRNA vaccines from Pfizer and Moderna administered in our country until last December 14, 2021. According to the 11th Pharmacovigilance Report on Covid-19 Vaccines from Spanish Agency for Medicines and Health Products (Aemps)the last one that collected these reactions, 240 cases were counted after the administration of 51 million doses of Pfizer and 81 notifications after the inoculation of about 9.5 million doses of Moderna’s serum.
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