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Breast Cancer Patients Who Received Chemotherapy at Higher Risk of Lung Cancer, Study Finds





Study: Breast Cancer Patients Treated with Chemotherapy at Higher Risk for Lung Cancer

Increased Lung Cancer Risk for Breast Cancer Patients who Underwent Chemotherapy, Study Finds

Women with breast cancer who have received chemotherapy are at an increased risk of developing lung cancer, a new study suggests. The study, conducted by Epic Research, a health data group based in Delaware, found that women who have undergone chemotherapy have a 57% higher lung cancer risk compared to those who received radiation. Additionally, patients who received endocrine therapy had a 171% increase in lung cancer risk compared to those who received chemotherapy.

Primary Lung Cancer Common in Women Previously Diagnosed with Breast Cancer

The study also revealed that primary lung cancer is more prevalent in women who have had a previous breast cancer diagnosis, compared to those who have not. The research team at Epic Research found that breast cancer patients, especially those who received chemotherapy, have the greatest risk of developing subsequent primary lung cancer.

Comprehensive Study Considering Two Million Women

The findings of the study are based on an extensive analysis of more than two million women between the ages of 50 and 84 who received screening mammograms between 2010 and 2023. The analysis excluded patients with an elevated breast cancer risk due to a past diagnosis of breast or lung cancer, those who had been recently screened, and those who started mammogram screenings prior to the age of 50.

Importance of Vigilance and Risk Monitoring for Breast Cancer Patients

While the study suggests a correlation between breast cancer, its treatments, and the development of lung cancer, the researchers emphasize that not all breast cancer patients will develop lung cancer. However, breast cancer patients, especially those who have received chemotherapy, are advised to monitor and be vigilant for the signs and symptoms of primary lung cancer.

Researcher Perspective on Increased Genetic Risk and Environmental Factors

Experts in the field have suggested that one cancer may put individuals at higher genetic risk for developing other types of cancer. Factors such as cancer gene mutations, environmental toxins, and the side effects of breast cancer treatments like chemotherapy may contribute to the increased risk. More research is needed to establish the exact causes and relationships between breast cancer and lung cancer.

Advances in AI and Disease Detection Platforms

Advancements in artificial intelligence and disease detection platforms are enabling the incorporation of multi-modal data in predictive algorithms, potentially improving risk identification and management. Companies that integrate both structured and unstructured electronic health record data with conventional imaging have better predictive performance in identifying patients at higher risk. However, further integration of electronic health record data is considered essential in detecting patients at the highest risk for lung cancer.

As always, it is advisable to consult with healthcare professionals and continue following standard healthcare guidelines for breast cancer screening and management.


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