A new study has developed an 11-factor dementia risk score with the ability to accurately predict the development of dementia up to 14 years before onset. The researchers called this tool the UK Biobank Dementia Risk Score (UKBDRS).
The study included 220,762 participants with an average age of 60 from the UK Biobank and followed their progress for 14 years. The researchers analyzed 28 risk and protective factors related to dementia and identified 11 key factors that predicted dementia risk with up to 80% accuracy.
The 11 factors are:
age; level of education; family history of dementia (parents); material deprivation or poverty; history of diabetes; AVC (cerebrovascular accident); depression; hypertension (high blood pressure); high cholesterol; the fact of living alone; the fact of being a man.
These factors include age, level of education, family history of dementia (parents), material deprivation or poverty, history of diabetes, stroke, depression, high blood pressure, high cholesterol, living alone and male gender.
The UKBDRS was able to predict the incidence of dementia in 80% of individuals in the UK Biobank study and in 77% of cases in the Whitehall II study. This score achieved comparable results to a dementia-relevant genetic test called APOE.
Although the study provides a useful screening tool for dementia, there are limitations, such as the lack of a clinical diagnosis of dementia in the study cohort and significant differences between the two groups of participants. However, this tool can help identify dementia risk early and develop prevention strategies.
It is also important to emphasize that dementia is a complex condition and that there are many factors that can contribute to its development. A comprehensive approach to dementia prevention and management is therefore essential.
Source: 360medical.ro
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2023-09-04 19:46:16
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