A new cause of immune dysfunction in HIV patients, identified as optic neuritis, has been discovered by Mahidol University.

Among the diseases caused by vision disorders. in addition to the symptoms “Diabetic eye disease” or “glaucoma” that are common. There is also “optic neuritis” that can threaten people, even people with immunodeficiency virus (HIV), if not adequately monitored.

assistant professor Dr. Panittha Chindara, medical professor at the neurology unit Department of Internal Medicine, Faculty of Medicine, Ramathibodi Hospital Mahidol University and a research team which is a collaboration within the Faculty between neuroscience Department of Internal Medicine and the Department of Ophthalmology as the “wisdom of the land” discovered a new type of immunity that causes optic neuritis And the findings have been published in the world-class academic journal “Dove Press Journal” which is ranked in the Top 1% of the world.

A study was conducted in 171 patients with optic neuropathy at Ramathibodi Hospital, with an average age of 45 years for 10 years. The new type of immunity that causes “Optic neuropathy” that the research team discovered for the first time in the world is called “Anti-Jo1” (Anti-Jo1 Associated-optic Neuritis), which looks more and more inflammatory. from one eye to the other Some may take several months. It can be treated with steroids. and drugs that press the landscape for a long time

However, Assistant Professor Dr. Panitthachindara further explained that “Optic neuritis” is a disease that occurs in the area of ​​the nerves that connect the eyes and the brain. with blurred vision in the early stages and even the incidence of “Optic neuritis” is found to be less than 2 cases per 100,000 people, but should not be complacent as it can cause severe vision loss.

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In addition, the research team has conducted a study in HIV patients, making the world of medicine see. The “reflex” of higher immunity But it might have the opposite effect.

to increase surveillance in patients with such diseases In general, HIV patients must take care of themselves by testing the body’s antibodies or “CD4” (Cluster of Differentiation 4) to have a constant value between 500 – 600 cells per 1 cubic milliliter. from taking anti-HIV drugs regularly

While a study in HIV patients by the research team found that the cause of the complications as well. “Optic neuritis” in HIV patients, in addition to being an effect of infection due to reduced immunity But it may be from the case of HIV patients with increased immunity to “reactions” (Immune reconstitution inflammatory syndrome), which can be treated symptomatically with steroids considered by a medical professional. This group of patients usually has a good prognosis.

Just keep observing the symptoms yourself by covering each eye with your hands. Then try to read books and look at different colors. to observe whether the visual potential has decreased or not along with comparing to see the difference in vision of each eye as well It will allow everyone to be far away from the risk of developing optic neuritis in severe stages.

Follow interesting news from Mahidol University at www.mahidol.ac.th

Interview and news writing by Thitirat Dechprom, public relations (specialized in corporate communication) General Administration Division office of the president Mahidol University Tel. 0-2849-6210

Source: Mahidol University

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