In the midst of the anti-Covid vaccination campaign, many women on social networks wondered about the menstrual disorders they were experiencing. If the gynecologists ensured that most were of a short duration and without gravity, they are the subject of careful monitoring at national and European level since their detection.
These disorders can occur after vaccination with an mRNA vaccine, namely those from Pfizer/BioNTech and Moderna. As of April 28, the regional pharmacovigilance centers have analyzed 9,381 declarations of cycle disorders reported with the Pfizer vaccine, and 1,557 with the Moderna vaccine, reports the Medicines Agency (ANSM). The majority of these declarations were made by the patients directly, specifies the agency. To date, 58 million injections had been made in women with the Pfizer vaccine, and 12 million with that of Moderna.
But the lack of data does not yet allow a definite link of cause and effect to be established. For this reason, the Medicines Agency once again invited the women concerned to report on Tuesday. To do this, go on the portal of the Ministry of Healthby providing “the most detailed information possible in the declaration form”.
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The elements collected must allow “regional pharmacovigilance centers to carry out their assessment of declared cases in the most efficient way possible”, she indicates. At this stage, the adverse events most often remain “not serious” and generally manifest themselves in two ways: by abnormal bleeding (metrorrhagia, menorrhagia), and by delayed menstruation or amenorrhea, underlines the agency.
To date, the available data do not make it possible to describe the mechanism of occurrence of these menstrual cycle disorders, she adds. However, she cites several hypotheses such as reactogenicity (fever, headache, nausea, etc.) caused by vaccination which could, as during an infection, influence the hormones involved in the menstrual cycle. Or even a significant stress, caused by the act of vaccination, likely to disturb the hypothalamic-pituitary-ovarian axis which regulates the smooth running of the menstrual cycle.
