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Understanding the Link Between Hepatitis B and Kidney Disease: Symptoms, Risks, and Prevention

Hepatitis B virus can damage the kidneys. Be careful if you have bubbles in your urine and swollen feet.

In addition to being complicated by liver fibrosis, cirrhosis and liver cancer, patients with chronic hepatitis B may also develop kidney disease. Zheng Zhihui, a specialist in gastroenterology and hepatology, pointed out that one of the reasons is that the immune response of hepatitis B patients may affect the kidneys and form glomerulitis. As time goes by, the more hepatitis B affects the body, the greater the risk of kidney disease.

When hepatitis B patients reach middle age, they may develop three high blood pressure (high cholesterol, high blood pressure and diabetes). These problems also increase the risk of kidney disease. Hepatitis B patients are more susceptible to kidney disease due to the double impact of two high-risk factors: their own condition and age. Zheng Zhihui said, “If hepatitis B has entered an advanced stage and cirrhosis has developed, the risk of kidney disease will be higher.”

Gastroenterology and Hepatology Specialist Zheng Zhihui

Middle-aged and elderly citizens should check for hepatitis B

Hepatitis B virus can have a serious impact on overall health. In addition to patients paying attention to their health, Zheng Zhihui believes that citizens should also know whether they are infected with hepatitis B virus without knowing it. “Local residents born before 1986 to 1988, or those born outside of other places” Those whose parents did not receive the hepatitis B vaccine before giving birth should consider getting tested for hepatitis B.” A 70-year-old woman once sought medical treatment because of swollen feet. After seeing a nephrologist, she discovered that it was chronic hepatitis B virus infection complicated by renal failure. Globitis. On the doctor’s advice, people who were related to her were tested for hepatitis B, and it was discovered that her other siblings and her daughter were also infected with the hepatitis B virus.

Common mother-to-child transmission

The more common local route of hepatitis B infection is mother-to-child transmission, but related cases are decreasing because since 1988, the government has vaccinated all local newborns with hepatitis B vaccine; from 1986 to 1988, local children were also vaccinated with hepatitis B vaccine. In addition, pregnant women who are infected with hepatitis B virus can take antiviral drugs during pregnancy to reduce the viral load. In addition, injecting hepatitis B immune globulin into their babies after birth can greatly reduce the risk of infecting the baby.

Blood test to understand viral load and kidney function

Zheng Zhihui said that after hepatitis B patients are diagnosed, they should have regular blood tests and arrange imaging examinations such as ultrasound examinations. “A blood test can determine the amount of hepatitis B virus and liver enzymes, and an imaging examination can determine whether there is cirrhosis or liver cancer.” In addition, blood tests can also detect kidney function. Patients should also pay attention to whether there are symptoms of kidney disease, such as proteinuria. That is, there is bubbles in the urine, which cannot be removed even if you flush the toilet. In addition, proteinuria can cause protein loss in the body and cause swollen feet. If swollen feet occur along with proteinuria, the patient should be alert and seek medical advice as soon as possible.

Healthy diet

Control your disease well to avoid kidney dialysis

If the kidney disease is severe, the patient will need to undergo dialysis treatment (kidney dialysis). Zheng Zhihui reminds that to avoid this happening, hepatitis B patients need to pay special attention to their health. “The most important thing is to control the amount of hepatitis B virus. Patients should take antiviral drugs every day to suppress viral replication.” Zheng Zhihui said that Entecavir and Tenofovir (TDF or TAF) are the first-line hepatitis B antiviral drugs. If hepatitis B patients with poor renal function need to take entecavir or tenofovir (TDF), the frequency of medication may need to be adjusted, such as taking it every other day, or even once a week.

Tenofovir’s older generation drug, TDF, has certain nephrotoxicity. Long-term use of the drug may affect the kidneys and worsen kidney function. As for tenofovir’s new generation drug (tenofovir fosprata TAF), it will not affect renal function while effectively suppressing hepatitis B virus. “Therefore, doctors are very concerned about the renal function of hepatitis B patients. In addition to worrying about complications, it also affects drug selection and adjustment of drug dosage.” Zheng Zhihui said.

The original article was published on AM730

2023-10-26 20:29:50

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