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Top Psychiatrist Accused of Advocating for OTC Antidepressants Without Disclosing Pharmaceutical Ties




Top Psychiatrist Suggests Making Antidepressants Available Over-the-Counter

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Doctors have raised concerns over psychiatrist Dr Roy Perlis’ recent suggestion to make antidepressants available over-the-counter, particularly due to his failure to disclose his financial ties with pharmaceutical companies. In an opinion piece for STAT News, Dr Perlis argued that the increased accessibility of mental health medication is crucial, pointing out that an estimated 50 million Americans may benefit from such drugs. However, experts have criticized his omission of potential side effects and his associations with antidepressant manufacturers, calling them “tedious and unprofessional”.

Advocating for Greater Access to Mental Health Medication

In the opinion piece, Dr Roy Perlis emphasized the need for accessible medicine for mental health conditions while stating the efficacy and safety of antidepressants. Drawing attention to the social stigma often preventing individuals from seeking help, Dr Perlis argued that over-the-counter antidepressants would be particularly beneficial. However, his comments aroused concerns regarding his lack of disclosure and the potential risks of antidepressants.

Expert Criticism and Links to Pharmaceutical Companies

Dr Perlis has faced criticism for his potential conflict of interest, with experts questioning the validity of his article. Dr James Davies from the University of Oxford stated, “Why can’t this psychiatrist… declare his numerous drug company ties?” Dr Perlis has disclosed ties to various antidepressant manufacturers in his research papers, which include receiving personal fees and consulting fees from companies such as AstraZeneca, Bristol-Myers Squibb, Eli Lilly and Company, GlaxoSmithKline, and Pfizer.

The Debate Surrounding Antidepressants

While Dr Perlis argues for over-the-counter antidepressants, other medical professionals and researchers hold contrasting views regarding their benefits. Studies have shown that around 40 to 50 percent of individuals with depression and anxiety experience improvements with antidepressants. However, about 60 percent of patients may not respond to these medications, and side effects can include nausea, vomiting, diarrhea, dry mouth, and sexual dysfunction. Concerns have also been raised about potential psychological symptom exacerbation and long-term effects.

Expanding Over-the-Counter Medications

Dr Perlis’ opinion piece comes as the accessibility of medications is being reconsidered. The recent availability of the contraceptive pill, obtained without a doctor’s prescription, has caused significant conversation. Advocacy groups and medical organizations have supported this change, and calls have been made for other medications, like anti-nausea medication and EpiPens, to be made available without a doctor’s order. Dr Perlis has been approached for additional comment regarding the concerns raised.

Side effects of antidepressants

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Monthly antidepressant dispensing rate

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