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The Silent Danger: The Relationship Between High Blood Pressure and Dementia

On September 23, 2023, reporters reported that Dr. Teerawat Hemajutha, head of the Emerging Disease Health Science Center Faculty of Medicine Chulalongkorn Hospital posted on Facebook Thiravat Hemachudha stating…

30 to 40 high blood pressure is not manageable. Definitely dementia.

High blood pressure It is a silent danger that people are not interested in. There is often a misconception that there is no headache at all. There is no need to measure blood pressure.

Not having a headache This is because blood pressure gradually increases. Climb up the level little by little. There will be no abnormal symptoms at all. And finally The soft blood vessels will begin to harden with or without tartar. and leads to coronary artery disease, coronary artery disease, and heart attack Cerebral hemorrhage causing paralysis

This villain has been accumulating for 10 years and gradually reveals itself.

High blood pressure causes changes in the brain. There is increasingly clear evidence. from brain computer examination in various ways They found a clear link between uncontrolled high blood pressure from age 30 to 40 and Alzheimer’s disease pathology. and other dementias and abnormal changes in the white matter of the brain By measuring the movement of water along the fibers of the brain From one location to another (fractional anisotropy), the efficiency in controlling blood supply to different parts of the brain in each situation. and the space around the blood vessels in the brain that acts as a drain for waste from the brain to be discarded and the amount of free water

Changes in the brain tissue, brain fibers, and blood vessels in the brain These abnormalities accumulate over time. Since middle age, blood pressure has not been controlled. with ages ranging from 30 to 40 years

high blood pressure The upper level is 130 and the lower level is 80. In Americans, it is estimated that at least 44 to 46% have high blood pressure, with men more frequently than women. But after the age of 65, women begin to experience higher blood pressure than men due to menopause. Lack of estrogen

Knowing and realizing the importance of controlling blood pressure from the beginning It will greatly reduce the burden of having to take care of your health.

The study, reported in the Journal of the American Medical Association JAMA network open April 3, 2023, used data from the Kaiser healthy aging and diverse life experiences (KHANDEL) project and the study of healthy aging in African Americans (STAR), which included Asian populations. Blacks, whites, and Latinos. It is hypothesized that blood pressure that occurs between the ages of 30 and 40 will have an impact on biological indicators that indicate dementia. and stability in the condition of the white matter of the brain, which is composed mainly of nerve fibers.

By evaluating with brain computer images

Study population from both projects Assessments began between 1964 and 1985 and have been followed ever since. Until 2017 and 2021, the population in this study was 427 people.

The results of the study found that Elderly people around 75 years of age, especially men. There will be an abnormality in the brain. If you have uncontrolled high blood pressure when you’re still in your 30s and 40s, compared to people who don’t have high blood pressure.

The abnormality that is clearly seen is The volume of the gray matter of the cerebral cortex (cortex) has collapsed, including the frontal and temporal lobes, causing the volume of the brain tissue to decrease. and made it appear that the hydrocephalus was larger. and there are abnormalities in the white matter of the brain It is measured by the efficiency of connecting different parts of the brain (brain connectivity) and free water as mentioned above.

This study, although the population was not large, But it has a good following. Although there may be limitations to the study of brain computers, It will be done at a single point in time.

But the results of that study May show differences between males and females. In women, it was considered possible that female hormones could protect against the effects of high blood pressure on brain atrophy. Until the hormones run out and women seem to have differences in the locations of their brains that are affected by pressure compared to men.

A 5 mm increase in systolic blood pressure was associated with a shrinking volume in the temporal lobe, while a 5 mm increase in systolic blood pressure was associated with a wrinkled parietal lobe. (parietal cortex) more

The study’s results are consistent with a report that analyzed about 30 studies that found high blood pressure at a young age. Related to brain degeneration in the frontal, temporal, and parietal lobes. and the inner temporal lobe, called the hippocampus. That is where current memory or short-term memory is stored. And several other studies have found a relationship with changes in the white matter of the brain as well.

All these things This indicates the importance of screening. Or screen for health conditions from young people reaching the age of 30 years and over and quickly control them.

However, this does not mean only about pressure alone. But it is about weight which we call body mass index and fitness condition. Paying attention to exercise

You must absolutely not start smoking and if you are still smoking you must quit immediately. It’s called broken cigarettes because no one has died from breaking cigarettes.

If you don’t know how to drink alcohol, you don’t have to start. If you are drinking, you can reduce the amount to drink for health, which is no more than 30 grams per day. This can be calculated from the percentage of alcohol. to the volume of the drink and as close to vegetarian as possible.

Just like this, Thailand, Thai people will be completely prosperous and will not have to waste the country’s budget. Go treat Thai people who are full of sick people. And also when will we be able to manage toxic dust, air pollution, and food from contaminated chemicals?

2023-09-23 10:10:48

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