Since the Corona virus began to spread in the United States, scientists have been solving many puzzling aspects of how the new Corona virus attacks the lungs and other parts of the body.
A study published in the journal revealed Nature Communications, That silent hypoxia is likely the result of a set of biological mechanisms that may simultaneously occur in the lungs of patients with Korna.
What is considered one of the biggest and most dangerous mysteries to life is how the virus causes “silent hypoxia”, a condition in which levels of oxygen in the body are abnormally low, which can damage vital organs irreparably if it is not detected for a long time. .
The biomedical engineers at Boston University and collaborators from the University of Vermont have begun to solve this puzzle. Emphasizing that although some patients suffer from a dangerous decrease in oxygen levels, many people with severe cases of Corona do not sometimes show symptoms of shortness of breath or difficulty breathing.
Silent oxygen –
In coronavirus patients, the infection is thought to damage the lungs first, making parts of them unable to function properly, and these tissues lose oxygen and stop working, and they no longer flood the bloodstream with oxygen, causing silent hypoxia.
Some Coronavirus patients witnessed what some experts described as levels of oxygen in the blood that were “incompatible with life.” To help get to the bottom of the causes of silent hypoxia, biomedical engineers at Boston University used computer modeling to test 3 different scenarios that help explain how and why they stop. The lungs are all about providing oxygen to the bloodstream.
Usually, the lungs perform the life-sustaining task of gas exchange, providing oxygen to every cell in the body as we breathe and rid us of carbon dioxide every time we exhale.
Healthy lungs keep blood oxygenation at a level between 95 and 100% – if it drops below 92%, this is a cause for concern and the doctor may decide to intervene with supplemental oxygen.
The researchers first looked at how it affects COVID-19 The ability of the lungs to regulate the direction of blood. Usually, if lung areas do not collect much oxygen due to damage from infection, the blood vessels in those areas will constrict.
This is actually a good thing the lungs have evolved to do, because it forces blood to flow through the oxygen-filled lung tissue, which is then circulated throughout the body.
But according to the researchers, preliminary clinical data indicated that the lungs of some patients COVID-19 The ability to restrict blood flow to already damaged tissues was lost, and in turn, those blood vessels were likely to open further – something that is difficult to see or measure on a CT scan.
Using a mathematical lung model, the team tested this theory, and revealed that until the levels of oxygen in the blood drop to the levels observed in patients COVID-19The blood flow must be much higher than normal in areas of the lungs that are no longer able to collect oxygen, which contributes to low levels of oxygen throughout the body.
Next, they looked at how blood clotting affected blood flow in different areas of the lung when the lining of blood vessels became inflamed from an infection. COVID-19In the lungs, blood clots can form so small that they cannot be seen on a medical examination.
They found, using computer modeling of the lungs, that this may induce silent hypoxia, but that it alone is unlikely to cause oxygen levels to drop to the lowest levels in patient data.
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