20:24 28.01.2020(updated 8:25 PM Jan 28, 2020) Short url
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The ketogenic diet, which continues its triumphant march around the world, has an effect only in the short term and a negative impact begins to appear after about a week, American researchers said.
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Results of a new study by researchers at Yale University and published in the journal Nature Metabolism reveal that the ketogenic diet, which provides 99% of calories from fat and only 1% from carbohydrates. carbon, has beneficial effects only for a certain time.
Scientists carried out an experiment on mice and discovered that this diet was beneficial for health, but only for a short period. After a week, its impact became negative.
The positive effects
These results, both positive and negative, are associated with gamma delta T cells, immune cells that protect tissues, reduce inflammation and lower the risk of developing diabetes.
“A ketogenic diet encourages the body to burn fat. When the body’s glucose levels drop following a low-carbohydrate diet, the body acts like it is going to face hunger, although it is not, and starts burning. fats instead of carbohydrates. This results in the formation of ketones that provide an alternative source of fuel, “said Vishwa Deep Dixit of the Yale School of Medicine who led the study.
When the body burns these ketone bodies, the tissue-protecting gamma delta T lymphocytes are distributed throughout the body which, according to experiments carried out on mice, improves the metabolism and reduces the risk of diabetes.
Negative effects
After more than a week, the mice began to consume more fat than they burned, causing it to be stored.
“Their protective gamma delta T cells got lost in the fat,” says Vishwa Deep Dixit.
“The results of our study highlight the interaction between metabolism and the immune system and show how the immune system coordinates the maintenance of healthy tissue functions,” said one of the study’s co-authors.
A great test needed
Researchers now have a better understanding of how organs function during the ketogenic diet and why it produces beneficial effects for a limited time.
“Before such a diet can be prescribed, it is important to carry out a large clinical test under controlled conditions in order to understand the mechanism of metabolic and immunological benefits, as well as the possible harm it could do to overweight and prediabetic people. “Warns Vishwa Deep Dixit.
However, the fact that the ketogenic diet can be followed from time to time, for short periods, is good news, he says.
“Who wants to diet all the time?” He asks to conclude.
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