Indonesia, dr. Jeffry Beta Tenggara, Sp.PD-KHOM.”>Meanwhile, in patients with advanced or metastatic breast cancer, i.e. there has been spread to other organs such as the lungs, liver and bones, for example with positive HER2, there are a number of therapeutic options that can be used. given to the patient, one of which is targeted anti-HER2 therapy.
This therapy aims to inhibit the action of the HER2 protein that plays a role in the growth and spread of cancer, such as giving trastuzumab, or a combination of pertuzumab and trastuzumab. In this therapy, side effects that need to be monitored include heart function, injection reactions, gastrointestinal side effects and allergic reactions.
Another therapy is chemo to kill cells that divide rapidly, including cancer cells. The most common side effects of this therapy include disturbances in blood cells and gastrointestinal tract, hair loss, disorders of peripheral nerves and heart function.
Then, if the patient has a positive hormone receptor (ER/PR positive) then hormonal therapy can be given which is useful in inhibiting the production or work of female reproductive hormones. Side effects that can appear are symptoms such as menopause, heart function and ostroporosis.
“In an advanced stage, metastatic, then the administration of anti-HER2 onwards. Until when Don’t know. This is another challenge, financial problems are the main problem because as long as there is a good response, it must be continued,” said a specialist in internal medicine consultant hematology oncology from the University of Indonesia, dr. Jeffry Beta Tenggara, Sp.PD-KHOM.
– .
