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Study Finds Increased Cancer Risk in Family Members of Men Without Sperm

For men without sperm, the risk of familial joint cancer is 156%, and the risk of soft tissue sarcoma is 56%.

Entered 2024.02.23 17:00 Entered 2024.02.23 17:00 Modified 2024.02.23 17:04 Views 38

Family members of men without sperm in semen have a 156% chance of developing bone and joint cancer, a 56% chance of developing soft tissue sarcoma, a 27% chance of developing uterine cancer, and a 60% chance of developing Hodgkin’s lymphoma. , the likelihood of developing a thyroid tumor was 54% higher. [사진= 게티이미지뱅크]A new study has found that families of infertile men with low sperm count are at increased risk of cancer. This is what the health and medicine webzine ‘Health Day’ reported on the 22nd (local time) based on a paper by researchers at the University of Utah published in Human Reproduction.

Professor Jomie Ramsey of the University of Utah, who led the study, said the exact link between cancer risk and male infertility is not yet clear, but “by identifying families with similar cancer patterns, we may be able to discover factors that are associated with both infertility and cancer.” He said. Previous research has noted a link between low sperm count in men and familial cancer risk, but the size of the effect has not been studied, he said.

Researchers collected semen sample analyzes from 786 men who visited fertility clinics in Utah and compared these results with samples from nearly 5,700 men known to be fertile. 426 people had azoospermia and 360 people had oligospermia (less than 15 million sperm per 1 mL of semen).

The researchers searched for statistics on the history of cancer among the men in the entire group and among their first-degree relatives. Among men without sperm in their semen, 12 out of 13 family members had a higher risk of at least one type of cancer. The results were similar for men with very low amounts of sperm in their semen. It was revealed that all 12 families connected to this man had a higher incidence of cancer.

Family members of men without sperm in semen have a 156% chance of developing bone and joint cancer, a 56% chance of developing soft tissue sarcoma, a 27% chance of developing uterine cancer, and a 60% chance of developing Hodgkin’s lymphoma. , the likelihood of developing a thyroid tumor was 54% higher.

The researchers found that family members of men with oligospermia had similar risks, including a 143% increased risk of bone and joint cancer, a 16% increased risk of colon cancer, and a 134% increased risk of testicular cancer. The only exception was that the risk of esophageal cancer was found to be 61% lower.

The range of risk varied greatly between families. For example, among men with low sperm counts, the risk of developing testicular cancer varied from 4 to 24 times depending on family cluster.

“We identified some unique patterns of cancer risk in families of men with low fertility,” Professor Ramsey said. “Sharing patterns of cancer risk among family members suggests common genetics, environmental factors, or health behaviors,” he said. This study “helps us assess cancer risk in families and provide improved patient counseling.” “It can be done,” he said.

The paper can be found at the following link:

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2024-02-23 08:00:38

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