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Side effects of the Janssen vaccine

Janssen’s vaccine received on March 11 the authorization for emergency use in all countries of the European Union for citizens over 18 years of age by the European Medicines Agency. This vaccine It is administered through a single dose, which will predictably increase the rate of vaccination.

The vaccine, which will not arrive in Spain until April, is composed of an adenovirus modified to include the SARS-CoV-2 protein S. This substance is what the virus uses to enter the body and transmit the infection to the rest of the cells, so Its previous introduction into the body allows the immune system to create antibodies against the disease.

Its administration from an injection into the muscle of the upper arm can cause side effects., either at the site of the puncture or on the rest of the body.

According to Centers for Disease Control and Prevention (CDC), at the injection site, the Johnson & Johnson vaccine can cause pain, redness, and swelling. The pain at the puncture site is the most common side effect since they suffered it 48,6% people during clinical trials.

In the rest of the body, the side effects that can occur are tiredness, headache, muscle pain, chills, fever, and nausea. The most frequent are the headache (38.9%), fatigue (38.2%) and muscle pain or myalgia (33.2%).

All side effects were reported with more often by younger people (18-59 years) than by older people. Most were reported in the first seven days after injection and were mild or moderate.

Who should not get vaccinated?

According to the CDC, they should not receive this vaccine those who have had a severe or immediate reaction (anaphylaxis) to any of the ingredients in the vaccine, which are the following: Recombinant non-replicable adenovirus type 26 expressing SARS-CoV-2 protein S, citric acid monohydrate, trisodium citrate dihydrate, ethanol, 2-hydroxypropyl-β-cyclodextrin (HBCD), polysorbate-80, and sodium chloride.

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