Those who have already had Covid should not be vaccinated because it has natural antibodies. He said it Giuseppe Ippolito, scientific director of the Spallanzani Institute, infectious disease specialist of the Scientific Technical Committee, also spoke on Radio. If anything, you will have to check the level of antibodies and when these fall you can consider a vaccination, explained Ippolito. The Genoese infectious disease specialist has the opposite opinion Matteo Bassetti who on Facebook claims the need to vaccinate both those who have never had the SarsCoV-2 infection and those who have already done it because it is not known how long the antibodies last.
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Subjects who do not have priority
When the goal ofimmunization with a vaccine, the debate opens on who should receive it. At the appropriate time that those who have had the disease do not get vaccinated. It will be appropriate to do this only once we have data on this sub-group of subjects. In any case, these patients have a low priority: It is reasonable to assume that they are protected from re-infection or, at least, from the complications of infection, al Courier service Giuseppe Nocentini, immunopharmacologist of the University of Perugia, member of the Italian Pharmacology Society.
The antibodies we measure with serological tests on the blood they can decay after a few months, it would mean self-monitoring about every three months and decide for yourself whether to get the anti Covid vaccine, an impractical path.
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They could be a defense boost
And all those who don’t really know if they’ve had the coronavirus? There are two types of people: who has had Covid and knows it and who has had Covid but does not know it, because he got it in shape asymptomatic. About half of the people who have made Covid do not know they have done it, especially in areas such as Lombardy – he says Sergio AbrignaniProfessor of General Pathology at the State University of Milan and director of the National Institute of Molecular Genetics Romeo and Enrica Invernizzi -. Since we’re not going to do the serology on everyone we vaccinate, of course we will have a part of the vaccinated population that has already had the infection. There is no immunological evidence for now that those who have had the natural infection should not be vaccinated, on the contrary it could be an upgrade of the immune response. Most vaccines have multiple doses: we could consider natural infection as the first dose and therefore, where we knew of a previous Covid positive, do the first vaccine as if it were the “second dose”, once.
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No immunological problems
So whoever has been sick can ask to be vaccinated to be safe? I would vaccinate them. Certainly they would not have priority, as a choice from the logistical point of view, but from an immunological point of view there is no problem – Abrignani reiterates -. Also why we don’t know how long natural immunity lasts and it seems to me to be more complex to go and measure the antibodies of those who have been infected than to vaccinate these people. It also happens with other vaccinations, hepatitis B and other infections. We also do the flu vaccine to those who have had the flu.
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It will also be offered to the vaccinated
Of the same opinion Alberto Mantovani, scientific director of Humanitas and emeritus professor of Humanitas University. First of all, it will be impossible to screen people exposed to the new coronavirus, he told Adnkronos. Furthermore, generally the immunity conferred by the vaccine is much higher than that acquired naturally by those who came into contact with the pathogen. The vaccine will also be offered to people who have already been exposed to Covid, Mantovani believes correct. In the interview granted to Courier service explains that the immunity given by the vaccine is higher than the natural one: There is not the slightest doubt: the levels of the immune response observed in the vaccinated are far higher than those observed in the vast majority of infected subjects. The idea has spread that natural infection is good “training”, but it is not. For example, measles clears the immunological memory towards other infectious agents for two years. If I get the vaccine I am protected from measles and at the same time have a reduction in the incidence of other respiratory infections.
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December 3, 2020 (change December 3, 2020 | 15:50)
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