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SARS-CoV-2 virus mutations exist in Indonesia, 3 of them in DIY-Central Java

KOMPAS.com – Research related to the corona virus continues to be carried out by a number of researchers in Indonesia in various places. In the process they discovered their existence mutation of the corona virus.

The research, one of which was carried out by the Genetic Working Group Team of FK-KMK UGM, examined the Yogyakarta and Central Java regions.

They succeeded in identifying the Whole Genome Sequencing (WGS) of four isolates from Yogyakarta and Central Java.

The results have also been published on GISAID.

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Head of Genetic Working Group, FKKMK UGM, dr. Gunadi explained that currently his team has only examined four samples.

“Only four of our samples were successfully analyzed for their full genome. Of the 4, 3 of them contained the D614G mutation,” he said when contacted. Kompas.com, Wednesday (2/8/2020).

As many as 3 of them containing the D614G mutation were found in Yogyakarta and Central Java.

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Higher infectivity

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Gunadi said the D614G mutation in the SARS-CoV-2 virus had an infectious power 10 times higher than other types.

“It turns out that the virus containing the D614G mutation has 10 times the infectious power,” he said.

In addition, isolates containing the D614G mutation have spread throughout the world, namely 77.5 percent of the total 92,090 isolates.

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Gunadi said that currently in Indonesia, 9 out of 24 isolates published in GISAID contain the D614G mutation.

He said, previously a researcher in the UK had researched and published it in the journal Cell.

The researchers compared viruses that mutated and did not.

The virus containing the D614G mutation has an infectious power 10 times greater than other types. However, this virus mutation is not related to severity.

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Not representative yet

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Gunadi also explained that the numbers researched by Indonesia were not yet representative to describe what was happening in Indonesia.

“Of course it is not representative, if we compare it with data from GSAID, there are around 92,000 full-genomes or more, we are far away, “he said.

So that in the future there will be further studies.

He said that if a minimum of 1 percent is needed, then his party needs to examine 1,000 samples full genomes.

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With the detection of the D614G mutation of the SARS-CoV-2 virus, according to Gunadi, all parties must be more disciplined in implementing health protocols, such as washing hands, using masks, avoiding crowds, and so on.

As of September 1, the total number of Covid-19 cases in Indonesia reached 177,571.

A total of 128,057 people have recovered and 7,505 people died.

Also read: Study: Coronavirus Detected in Children for Weeks

photo-infographic" style="max-width:100%"> KOMPAS.com/Akbar Bhayu Tamtomo
Infographic: Prevention of Corona Virus Transmission


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