Large swathes of Ukraine suffer from power outages after a wave of Russian raids.
Nearly half of Moldova was without electricity, although the Russian shelling did not reach it.
The attacks in Ukraine have targeted critical infrastructure in the capital Kiev. Officials said six civilians were killed in the bombing.
Moscow has recently escalated its attacks on Ukrainian energy facilities, leaving half of the country’s electricity grid idle.
The company that manages Ukraine’s national electricity grid said damage to power generation facilities in recent weeks had been “enormous”, warning that Ukraine could experience prolonged blackouts during the winter months.
Early Wednesday, sirens blasted across Ukraine warning of an airstrike, followed by reports of explosions in several locations.
The Ukrainian Air Force said more than 70 cruise missiles were launched from Moscow, and Ukrainian defenses were able to intercept 51 of those missiles.
Ukrainian officials said Russia also launched five drones.
Ukraine’s nuclear company Energoatom said three of its nuclear reactors lost internet connection due to a power outage.
In the capital, Kiev, parts of the city have suffered from complete water and electricity outages, according to mayor Vitali Klitschko.
Lviv Mayor Andriy Sadovy said schoolchildren were taken to the bunkers with their teachers and parents were advised not to take their children outside before the sirens ended.
Prior to reports from Kyiv and Lviv, officials said western Ukraine had come under renewed attacks.
The Mykolaiv region governor said that many missiles were coming from the south and east.
Not far away, in the Zaporizhia region, a newborn baby died when a missile hit a maternity ward, according to the emergency services.
The finger of blame for this attack is pointed at Russia, which has yet to comment on any of Wednesday’s alleged attacks.
Ukrainian President Volodymyr Zelensky accused Moscow of “terrorist acts”.
Zelensky said he instructed his UN envoy to request an emergency meeting of the Security Council.
Meanwhile, more than half of Moldova suffers from power outages, Deputy Prime Minister Andre Spino announced.
Via Twitter, Spino said the targeting of Ukrainian infrastructure had caused “widespread blackouts” across Moldova.
Within a few hours, electricity was restored in most areas of the capital, Chisinau, where a third of the Moldovan population lives.
In response to the power outages in Moldova, the country’s president, Maia Sandu, said Russia had “left Moldova in the dark”.
Moldova has suffered widespread power outages following the Nov. 15 attacks on Ukraine, Deputy Prime Minister Spino said. Mobile phone networks have also been hit hard.
On the other hand, the European Parliament overwhelmingly approved a resolution deeming Russia a “state sponsor of terrorism”, which is not binding.
The resolution condemns what it describes as Russia’s “deliberate attacks against Ukrainian civilians and its destruction of Ukrainian civilian infrastructure in flagrant violation of human rights and international law”.
Parliament called on member states to take further steps to isolate Russia internationally and to toughen sanctions against it, and called for work to develop a legal framework that allows member states to designate state sponsors of terrorism.