Researchers Find Sources That Make Toothache When Eating Ice Cream

Suara.com – Scientists believe that they have found a reason why biting ice or drinking something very cold can cause toothache.

They find the cell and the signal is on sensitive teeth which can detect temperature drop and trigger tooth ache as well as a brain weapon.

People with tooth decay very prone to toothache because the pathways are open.

These findings allow researchers to know the target treatment new from rheumatic pain which can be in the form of toothpaste, tooth fillings, or chewing gum.

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“Once there are molecules to target, there are possible treatments,” said Katharina Zimmermann, lead author of the study published in the journal Science Advances this, was launched BBC.

The target the researchers found was called TRPC5, which is located on the odontoblast cells, located between the inner soft pulp and the dentin layer.

Enamel can’t taste anything, unlike the dentin which is the layer after it. Dentin is connected to the innermost pulp, where nerve cells live.

If the dentin is exposed, for example due to tooth decay or gum disease, painful stimuli such as temperature or certain fluids will cause pain.

“In human teeth with cavities and dental caries, we found a large number of TRPC5 channels. We therefore believe that engineered TRPC5 inhibitors, which can be applied locally to teeth via strips or gum, will be of great help in treating dentin hypersensitivity or toothache. “he continued.

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Zimmermann said in the future, TRPC5 blocking agents could be incorporated into toothpaste and dental products to prevent pain due to sensitivity.

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