Research Shows Exercise Can Reduce Age-related Fat Accumulation: Study Published in ‘Nature Aging’

[메디컬투데이=최재백 기자] It has been proven that exercise can reduce the accumulation of fat that occurs with age.

Research results have been published in ‘Nature Aging’ which show that exercise can reduce the accumulation of BMP (Bis (monoglycero) phosphate) lipids created with age.

After first discovering BMP in mouse tissue and human muscle, the research team discovered that BMP begins to accumulate in muscle tissue with age.

They examined 10 different tissues from young and old mice to see if there were any differences in lipids in the tissues according to age.

In addition, they said they performed muscle biopsies on young men and women between the ages of 20 and 30 and older men and women between the ages of 65 and 80 to identify BMPs accumulated in the muscles of older participants.

The researchers noted that BMP accumulates in human tissue in the same way as the results of animal experiments, and they tried to see if exercise could change BMP levels.

They studied 12 postmenopausal women between the ages of 45 and 70 and divided them into three groups: a ‘sedentary group’ who sat 14 hours a day, an ‘exercise group’ who exercised for one hour a day, or a ‘group’. who stood for 3 hours a day and walked for 2 hours a day. All female participants were obese and exercised less than 3 hours per week.

As a result of the study, the researchers found that BMP levels decreased in the exercise group even if the intervention period was very short.

They said that while much is known about the effects of simple lipids such as cholesterol on aging and disease (eg atherosclerosis), less research has been done on the effects of ‘complex’ lipids such as phospholipids on aging.

Through this study, they confirmed that BMP lipids can accumulate significantly in human muscles as people age, similar to the results of animal experiments, and concluded that they were able to lower BMP levels in postmenopausal women with exercise treatment. short term.

At the same time, the number of participants was small (12), only one type of substance was observed, and the exercise treatment period was short, so the long-term effect of exercise on BMP levels could not be determined. to confirm. In addition, it was noted that the data on whether each participant was taking lipid-lowering drugs was limited, so the potential impact of the drugs on BMP levels.

The research team predicts that future research will be needed to understand the increase in BMP levels in the body as a result of aging, focusing not on only on women but also on different populations, and to investigate whether the increase in BMP levels is a harmful response to aging or a compensatory response to damage due to aging.

They expected that studying complex lipids (fat) would help to understand age-related diseases and longevity. In addition, the importance of regular exercise to maintain mobility, improve cognitive function and sleep, and promote positive emotions and vitality was emphasized.

Medical Today Video Editing Team ([email protected])

[저작권자ⓒ 메디컬투데이. 무단전재-재배포 금지]