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Research on Osteoporosis in Space: Exploring Relief for Bedridden Patients

Research on osteoporosis in space, preparing to expand on providing relief to bedridden patients

Today is an era of growth in the space tourism business. as well as various innovative production industries that uses technology designed for life in space or equivalent extensively But the most important thing is not just preparing material things. But it is the preparation of “travelers” who must adapt to “No gravity” which is a condition that humans are not accustomed to.

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Prof. Dr. Narattaphon Phutthaphan, Director of the Institute of Molecular Biosciences and professor and researcher at the Calcium and Bone Research Unit (COCAB – Center of Calcium and Bone Research), Faculty of Science. Mahidol University said that the human body needs proper movement. Stay in a place where gravity is just right. The body will have a strong structure.

Especially in the bones Research from many countries has found clear bone abnormalities in both humans and animals exposed to the weightlessness of space for long periods of time. At least for 2 weeks or more.

This is because bones move under conditions without gravity. As well as other tissues such as fat, muscle, brain, etc., there will be a lack of “mechanical signals” or forces that will cause the cells to function. They are in perfect condition and can send signals to each other normally. In general, bone calcium mass is related to body weight. Under the condition of no gravity Body weight will disappear. Bones lose calcium quickly.

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Mahidol University has joined with the Geo-Informatics and Space Technology Development Agency. (Public Organization) or GISTDA – Geo-Informatics and Space Technology Development Agency (Public Organization) and the Japanese Aerospace Exploration Agency JAXA – Japanese Aerospace Exploration Agency have signed a research collaboration that leads to the creation of hypotheses of the risk of hypersensitivity. Osteoporotic bones of people who have lived in the weightlessness of space for long periods of time.

Under funding from The National Research Council (NRCT) has led to additional studies in addition to “Mechanical signals” to the bones, continuing to question the forces connected to other organs in the body, such as tissues and muscles in various parts Which is natural when humans are on the earth where there is gravity. You will feel the pressure. Or vibrations when movement occurs, such as walking, running, jumping, etc.

To answer the design of anti-osteoporosis drugs. that works precisely on point or activities that will help prevent the risk of osteoporosis for life both on Earth and in space of people who had to live in the weightlessness of space for a long time

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JAXA and GISTDA support researchers from Mahidol University, including Prof. Dr. Narattaphon along with Assoc. Prof. Dr. Yotchanan Wongsawat, Director of the Institute of Technology and Innovation Management (iNT) and full-time lecturers. Department of Biomedical Engineering Faculty of Engineering Mahidol University Studying the tissues of lab rats raised on the International Space Station.

In addition, under support from National Research Council (NRCT) and Mahidol University Provide an opportunity for the research team of Prof. Dr. Ratthaphon studies “mechanical signals” that connect to organs in other parts of the body, such as tissue, fat, intestines, and various muscles. All of which send signals to indirectly alter bone function.

It is time for Thai people to take a long-term view. Prepare to support a new way of life in space. Which is currently considered a “world issue” that every country is aware of. and give importance to all related aspects By developing basic science of the country to be strong Ready to open the world to make space travel an important destination. Especially to be an economic direction that will ensure the future of Thailand does not stray outside the world’s orbit.

By Prof. Dr. Naratthapon views that even in Thailand When it comes to preparing to live in space, we may not receive much attention these days. But if the results of such research are applied to create an understanding of the mechanisms that cause osteoporosis in “Bed-ridden patients” who lack movement and exercise causing less bone mass It is a similar phenomenon. And they have common ground with what happens in astronauts.

It may lead to a solution. and expand the results to the policy level that will have a positive impact on the development of the country’s public health system in the future. And what should not be overlooked is that space research has led to the parallel development of other technologies, such as smart materials. Future drug delivery systems, food, clean energy, etc., all of which will benefit humanity on Earth.

2023-10-15 01:52:10

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