What number of laboratories in Italy are able to finishing up gene sequencing at present? And, particularly. to do it with Subsequent Era Sequencing (NGS) applied sciences, which permit many genes (or very massive genes) to be sequenced concurrently in a short while? To reply these – and different – questions, the Nationwide Company for Regional Well being Providers (Agenas) carried out the primary survey of the genomics actions of accredited private and non-private constructions all through the territory, and revealed maps and information on-line. The platform is split into two sections: one regarding the laws carried out by the Areas, the opposite regarding the actions of the centres. The database stories, amongst different information, the 12 months during which genomic analyzes had been began, the kind of exams carried out and platforms used, the service exercise, the biobanks and the bioinformatic evaluation carried out.
Uncommon ailments, 1,000,000 euro fund for genomic exams
by Tiziana Moriconi
The mapping
Nicely, general 132 facilities (of which 99 public and 33 personal accredited) have transmitted info on their actions carried out with NGS platforms on behalf of the Nationwide Well being System within the two-year interval 2021-2022, for a complete of over 300 energetic laboratories (some constructions have multiple laboratory). Lombardy is the area with probably the most constructions (28) adopted by Sicily (15) and Lazio (13). The actions of the laboratories seem like divided into 4 totally different areas: medical genetics (with over 340 thousand samples analyzed within the two-year interval thought-about), microbiology (over 127 thousand samples), pathological anatomy (126 thousand samples) and scientific pathology (nearly 52 thousand samples). So far as pathological anatomy is worried, molecular oncological diagnostics reign supreme: nearly 65% of the samples analyzed involved this space. Moreover: 74 facilities perform actions underneath settlement for exterior events; 94 facilities additionally perform analysis actions, along with diagnostics: 19% of the analysis issues the oncology subject.
Precision drugs, nearly 300 million new mutations found
by Dario Rubino
The rationale for the reconnaissance
Genomic applied sciences are more and more enjoying a number one position in analysis and clinics, and are the premise of precision and personalised drugs. On this context, the Agenas survey is a part of the “Inter-institutional coordination desk for Genomics in Public Well being” and as a part of the implementation of the “Plan for the innovation of the Well being System primarily based on omics sciences”. The target – stories the company – is to acquire a mapping of regional organizational fashions, geographical accessibility, volumes, the kind of genomic analyzes carried out and the diffusion of NGS applied sciences. Final however not least, it additionally needs to encourage the creation of a community group and the sharing of regional experiences. At current, 11 areas have issued provisions to ascertain a community of laboratories that perform genomic analyses, and/or pointers for organizing the exercise; 7 areas are organizing whereas 3 are nonetheless at a standstill.
Tumors, genomic exams used little and badly
by Elisa Manacorda
#Precision #drugs #map #facilities #analyze #genome
– 2024-05-22 11:44:30
