Lynch Syndrome: The Little-Known Genetic Condition that Increases Cancer Risk

New Research Reveals Little-Known Syndrome Increasing Colon Cancer Risk

Colorectal Cancer Cases on the Rise among Younger Patients

In recent years, there has been a significant spike in the number of younger individuals developing colorectal cancer. This alarming trend has prompted experts to shed light on a little-known genetic condition that greatly increases the risk of developing various types of cancer, including colorectal cancer.

Understanding Lynch Syndrome

Lynch syndrome, a genetic disorder, makes individuals more vulnerable to several types of cancer. This inherited condition is characterized by a faulty mismatch repair system, which results in a higher risk of developing mismatches and abnormalities in cells.

In order to gain deeper insights about Lynch syndrome and its implications, the staff at Fox News Digital recently spoke with two experts on the subject.

Increasing Awareness for Early Detection and Prevention

The underdiagnosis of Lynch syndrome is a significant concern. According to Dr. Ajay Bansal, a gastroenterologist at KU Medical Center, 95% of patients with the condition are unaware that they are at an increased risk for a range of cancers. These potentially affected individuals are typically not aware that colorectal, uterine, ovarian, stomach, small bowel, kidney, bladder, and possibly brain cancer all pose a threat.

Due to the lack of symptoms associated with Lynch syndrome, patients often remain unaware of their condition until cancer develops. Recognizing the importance of early detection, Bansal and other experts emphasize the need for genetic testing.

Diagnosing Lynch Syndrome

Lynch syndrome can be confirmed through a blood or saliva test. Patients with a family history of multiple cases of colon cancer or other related cancers, or those with a family member with early-onset colon or uterine cancer, should consider undergoing genetic testing.

While universal genetic testing is not yet a common practice, patients who meet the criteria are recommended to undergo testing between the ages of 18 and 25.

Regular Screenings and Monitoring Essential

Since Lynch syndrome has no cure, early detection and preventive measures are imperative. Patients who test positive should undergo regular screenings, particularly colonoscopies.

In the general population, colonoscopies are typically recommended to start at the age of 45. However, those with Lynch syndrome should begin screenings at the age of 25 and repeat them every one to two years. This close monitoring aims to identify and remove polyps early or detect cancer at an early stage when it is more treatable.

While no definitive treatment exists for Lynch syndrome, ongoing research, like the clinical trial conducted by Dr. Bansal, highlights the potential of cancer vaccines in reducing cancer risk. Vaccines targeting abnormal cells in the colorectal and other associated organs offer hope for individuals with Lynch syndrome.

Raising Awareness – A Key Approach

Healthcare professionals encourage patients to discuss their family history with their primary care providers to identify potential genetic conditions, like Lynch syndrome. Regular discussions about family medical history and potential genetic testing offer an effective means of detection and preventive care. By recognizing the risks associated with Lynch syndrome, individuals can take the necessary steps to protect their health.

As more light is shed on the importance of early detection and preventive measures, the medical community is hopeful that increased genetic testing and ongoing research will help curb the development and progression of cancer in high-risk populations.