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Expert: Vaccines Are Still Effective Against Severe Covid-19 : Okezone News

MISSOURI – With soaring varian delta, various reports indicate that some people who have been vaccinated are still infected Covid-19 virus. However, these infections are mostly mild. All vaccines still work best by any measure.

“The vaccines are very effective in doing what we want, which is to protect people from serious illness and death,” said Bill Powderly, a health expert and director of the Institute of Public Health at Washington University, St. Louis, Missouri.

Recent infections in Israel have raised concerns that some vaccines are weaker against the delta variant. But Bill Powderly said the vaccine prevented the worst cases, as shown by the surge in the state of Missouri.

“They are witnessing infection the way the Israelis see it, in people who have been vaccinated. However, none of those infected were hospitalized. All hospitalizations, and unfortunately, all deaths, have occurred in people who have not been vaccinated.”

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Some vaccines are better than others at strengthening the immune system.

Moderna and Pfizer mRNA vaccines generally appear to produce the most antibodies, followed by viral vector vaccines: Johnson & Johnson, Oxford University-AstraZeneca and Sputnik V vaccines.

Vaccines using attenuated viruses such as China’s Sinovac and Sinopharm are at the lower end of the efficacy scale.

All vaccines produce sufficient antibodies against the original strain, but antibody levels play a more important role against new variants, said Peter Openshaw, professor of medicine at Imperial College London in an interview.

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“Perhaps with a slightly less potent vaccine that doesn’t induce a strong enough immune response, delta agents start to break through, but still provide protection against more severe disease,” he explained.

Deborah Fuller, a vaccine expert at the University of Washington, Seattle, Washington, said in an interview with VOA that Pfizer, Moderna, AstraZeneca, Johnson & Johnson and Sputnik V axins are all better than Sinopharm and Sinovac at activating the body’s second line of defense, called T cells. .

“Vaccines capable of inducing a backup immune response, such as a T-cell response, will provide better protection against various viral variants, than vaccines from inactivated viruses that induce only antibodies,” said Fuller.

Deborah added that the Sinopharm and Sinovac vaccines are very similar to the annual flu vaccine in that they are not perfect, but better than nothing, despite the complaints she hears every year.

“I hear people getting vaccinated, and they say, ‘Well, I’m never going to get vaccinated again because I still get sick.’ And my response is always: you know what? You will be much more sick, possibly hospitalized, if you are not vaccinated,” he explained.

He said all vaccines help slow the spread of the virus, which means fewer opportunities for dangerous variants to develop.

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