Weifu recently announced the results of the “National Community Dementia Epidemiological Survey”. The prevalence rate of dementia among elderly people over 65 years old in Taiwan is nearly 8%. It is estimated that there will be 350,000 people in 2024. In terms of gender, the prevalence of dementia is The prevalence of mental illness is 9.36% among women, which is higher than 6.35% among men. Xu Wenjun, chairman of the Taiwan Dementia Association, analyzed that women live longer (the risk of dementia increases with age), and women with Alzheimer’s disease are twice as likely as men. It is currently speculated that it is related to female hormones, but More empirical research is awaited.
Estrogen may help delay and prevent dementia
In “Estrogen Matters!” In the book “Grasp the Critical 10 Years, Improve Menopausal Discomfort, and Stay Away from Breast Cancer, Heart Disease, Osteoporosis and Dementia” (Traditional Chinese version published in February 2024), Avrum, an American medical doctor and oncology expert The doctor mentioned:
“Women are at higher risk of developing dementia because they live longer, and the chance of developing the disease increases sharply with age; but even after controlling for longevity, women are still more likely than men to develop the disease. Dementia – Two-thirds of Alzheimer’s patients are women… If estrogen plays a role in protecting neurons and glial cells in the brain, and the decline in estrogen is responsible for the One of the main reasons for the high incidence rate of Alzheimer’s disease is worthy of our attention.”
Dr. Avrum writes in “Estrogen Matters!” “The book states that, at least for women, estrogen is an option worth considering to reduce the risk of dementia, because “decades of research have confirmed that estrogen helps maintain cognitive abilities in postmenopausal women. , reduce their risk of Alzheimer’s disease.”
There are many brain and animal studies supporting that: in addition to stimulating neuron growth and increasing neuroplasticity, estrogen can also enhance memory, neurotransmission function, blood flow, glucose metabolism, and neuroprotective functions.
In real life, many studies have confirmed that estrogen can enhance or maintain women’s language ability, language memory, social and physiological functions in daily life. In addition, many observational studies have pointed out that estrogen users have a reduced risk of dementia and Alzheimer’s disease. Although the proportion of the reduction varies greatly, ranging from 24% to 65%, they basically point out that One key:
The results of the current research show that women must start estrogen treatment when they have just entered menopause and their brains are relatively healthy, which is more effective in reducing the risk of dementia. However, in order to fully exert this effect, at least they must take ten years.
“Estrogen is helpful in preventing or delaying dementia.”
Key timing for estrogen to prevent dementia in women
It should be noted that although hormonal therapy can help reduce the risk of various types of dementia, if a woman already has some degree of dementia when receiving hormonal therapy, the results of receiving the therapy will be mixed: short-term It may cause a small improvement in the condition, but it may be harmful in the long run. Therefore, women who start taking estrogen only after more than ten years of menopause, when their neurons have become unhealthy, may worsen the condition in the long run.
The results of the current research show that women must start estrogen treatment when they have just entered menopause and their brains are relatively healthy, which is more effective in reducing the risk of dementia. However, in order to fully exert this effect, at least they must take ten years. As for whether the protective function of estrogen can be extended to older ages after cessation of hormonal therapy, since insufficient research results have not been accumulated yet, we look forward to more research and observations in the future.
[Extended reading]
Source: Chinese Health Network
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2024-03-28 00:00:00
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