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A protein from cow’s milk protects against allergies

Cow’s milk that comes directly from the farm has special health benefits.

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Do. 25. Juni 2020

Children who grow up on a farm and drink unprocessed milk are less likely to suffer from allergies and asthma. It is believed that the farming environment trains the immune system and thus “farm protection” is created. Scientists at the Medical University of Vienna have now found that a certain milk protein is crucially involved.

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The scientists have conducted laboratory and animal experiments with beta-lactoglobulin, a protein that is found in milk. It seems to play a key role in “farm protection” against allergies: when beta-lactoglobulin is loaded with natural substances such as plant pigments from green grass, it could prevent the immune system of mice from developing an allergy. If the protein was not loaded, however, it acted like an allergen, as the researchers write in the journal “Journal of Allergy and Clinical Immunology”.

The researcher Dr. Franziska Roth-Walter explained that the beta-lactoglobulin loaded with natural substances brings its binding partners specifically to the immune defense cells, thereby preventing inflammation. The natural binding partners also prevent the IgE antibodies typical of an allergy from binding to beta-lactoglobulin protein, which is probably better tolerated by lactose-intolerant children.

Circumstances through which the natural attachment partners are lost, for example due to industrial milk processing or poor quality of animal feed, can therefore convert beta-lactoglobulin into an allergen. The researchers now hope that these new findings can be used to provide allergy protection beyond life on a farm.

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