KOMPAS.com – Gout is a natural compound produced by the body, so that its presence can be normal in the blood and urine.
However, the rest of the metabolism of food proteins that contain purines can also produce gout.
Therefore, the level of gout in the blood can be increased when one is consuming too much of the high purine foods.
Also Read: What is the Normal Rate of Normal Gout in Blood?
The level of uric acid in the blood of each person can be different, especially depending on age and gender.
However, in general, uric acid levels are normal in men which is below 7 mg / dL.
Meanwhile, uric acid levels are normal in women which is below 6 mg / dL.
Meanwhile, uric acid levels are normal before puberty, averaging about 3.5 mg / dL.
After puberty, uric acid levels in men increase gradually and can reach 5.2 mg / dL.
In women, uric acid levels usually remain low, and only rise after menstruation.
An increase in uric acid levels that exceeds the normal limit can be a cause of gout or gout.
In medical terms, high levels of gout in blood can be referred to as.
This condition is not only caused by unhealthy lifestyles, especially consuming too much food containing high purines.
Also read: 15 Foods That Cause Uric Acid Besides Bucking
Some other things can also trigger the condition.
Hyperuricemia can basically arise due to the production of excess uric acid or with a reduced disposal.
Launch various sources, here are some causes of high uric acid in addition to eating foods high in purines:
1. Disturbances in purine metabolism
Launch Book Rheumatism: Gout-hyperuricemia, gouty arthritis (2007) by Misnadiarly, the production of uric acid in the body or endogenous can be very excessive because of the disruption of innate purine metabolism.
2. Enzyme overactivity
Excessive uric acid production can also be caused by heteditary abnormalities, trait carriers, genes, or hereditary.
Hyperuricemia can also occur due to enzymatic overactivity phosphorbosyl pyrophosphate synthesis (PRPP-synthetic).
Also read: 12 Food Suggestions for Gout Patients
3. Consumption of certain drugs
Consumption of certain drugs such as pyrazinamide (anti-tuberculosis drugs), diuretic drugs or HCT, and salicylates can cause the removal of uric acid is greatly reduced.
This can occur due to the inability of the kidneys to remove excess uric acid from the body.
Meanwhile, spending through the intestine may also be reduced.
4. In famine
Starvation conditions such as fasting, too strict a diet and ketosis can cause uric acid removal is greatly reduced.
In this condition, the body’s lack of calories is filled by burning body fat. Ketone substances that are formed from burning fat, will inhibit the release of uric acid through the kidneys.
As a result, uric acid levels in the blood increase or hyperuricemia occurs.
5. Pregnancy poisoning
Pregnancy poisoning in pregnant women (toxemia) or possibly food poisoning can also cause uric acid removal to be greatly reduced.
Also read: 9 Fruits for Treating Gout
6. Exercise is too heavy
Launch Book Medicinal Plant Recipes for Gout (2012) by dr. Setiawan Dalimartha, doing too heavy exercise or too heavy activity can cause uric acid removal to be greatly reduced.
Exercise is too heavy the article can cause a buildup of lactic acid in the muscles so that the removal of uric acid
7. Combined
The occurrence of hyperuricemia can also be caused by a combination of increased endogenous purine production and high purine intake accompanied by decreased uric acid through the kidneys.
Also read: Is it true that drinking coffee can cause gout?
8. Certain medical conditions
Launch Book Easy Recipes to Stay Healthy (2009) by Dr. Handrawan Nadesul, in addition to disorders of purine metabolism, high uric acid can also occur due to certain medical conditions.
Here are some diseases or conditions that can cause hyperuricemia:
- Leukemia blood cancer
- Red blood cell excess disease polucytaemia
- The thyroid gland is too active (hyperthyroidism)
- High blood pressure
- Lead poisoning (lead)
- Obesity
- Abnormalities such as intestinal intolerance, glycogen-borne diseases, and glucose-6- deficiencyfosfat dehydrogenase (G6PD) can cause excess lactate production so that uric acid removal decreases.
High uric acid levels in the blood should be watched by anyone.
For a long time, hyperuricemia can be involved in body tissues, or joints.
In tissues and joints, the pile of uric acid will turn into uric crystals.
Also read: 8 Natural Ways to Reduce Gout
Dr. Handrawan Nadesul in his book, explained the form of the cretal veins resembling tiny-sized needles that appear under a microscope.
These crystals will settle if the cold, or the process of suppression.
That is the reason for the joints which are located somewhat to the surface of the skin, in addition to being exposed to the cold from the outside, are also vulnerable to stress, so more often formed urate crystals there.
Vein crystals are often found in the auricle, elbows, shoulders, wrists, knees, instep, heels, and most often in the big toe.
The pain that occurs in the joints and is caused by high uric acid is part of the symptoms of gout.
Also read: Is it true that drinking coffee can cause gout?
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