Health Cardiac hypertrophy, discovery of a factor regulating abnormal heart...

Cardiac hypertrophy, discovery of a factor regulating abnormal heart growth


An enlarged heart should be able to process more blood and generally have more power than a medium-sized heart, but reality tells us something else.
This is a real disease, called an enlarged heart, which can in turn be caused by various factors, including hypertension.

The heart muscle becomes thicker and harder over time until it reaches heart failure: the heart can no longer contract normally and pump the necessary amount of blood throughout the body.
A new study, conducted by researchers at the Lewis Katz School of Medicine (LKSOM) at Temple University, announces the discovery of a new key factor that would support the regulation of normal heart growth.

This regulator, called FoxO1, which is part of the Fox family of proteins, was described in a study published in Circulation. According to the researchers, this transcription factor binds to various genes found in heart cells and can lead to increased activation in growth signaling.

“Our observations mostly highlighted the underestimated mechanisms of pathological heart growth,” says Jessica Pfleger, director of the study. “From a therapeutic point of view, more work is needed to correctly target FoxO1, since it is intimately involved in the activation of many genes associated with heart growth.


Please enter your comment!
Please enter your name here

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Latest news

Charlotte de Turckheim: who are her three daughters Clara, Julia and Johanna?

Charlotte de Turckheim is the mother of three daughters: Clara, Julia and Johanna? But who are they? ...

He stamped the restaurant guest on the head with such force that he died. The court reduced his sentence

According to the Court of Appeal, it was a serious injury to health resulting in death, not a murder,...

SEP: the return to school will be on August 24 at a distance in conjunction with television stations President of Mexico, Andrés Manuel López Obrador, offers his morning conference from the National Palace, accompanied by the...

Corona virus research: enzyme boosts virus replication

Scientists at Goethe University Frankfurt have discovered a potential target for new anti-SARS CoV-2 drugs. According to a...

Must read

You might also likeRELATED
Recommended to you