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Why is the second dose of Pfizer’s COVID-19 vaccine more reactive than the first?

The vaccination campaign against him coronavirus progresses in Spain at a very good pace and this week it is expected to reach the 25 million immunized with the complete guideline. But, despite the fact that more than 23 million Spaniards have already received the second puncture of Pfizer, Modern the AstraZeneca there are still many doubts about the side effects of the same.

Héctor Castiñeira known on social media as ‘Saturated Nurse’ has tried to solve in Antena 3 all those questions that continue to arise about the COVID-19 vaccine.

With the approval of the AstraZeneca vaccine in our country, people began to talk about the first side effects of the sera against the coronavirus. The first puncture of this combination meant in its first weeks the cancellation of several teachers in the Community of Madrid due to discomfort derived from immunization. These effects They do not usually last more than 24/48 hours and are usually fever, headache, malaise etc.

However, with Pfizer Citizens say that the second dose gives a greater reaction than the first, something that Nurse Saturara attributes to a kind of cell memory. It is quite common for the second dose of the coronavirus vaccine to give more reaction than the first because activate that immune memory. Those cells are activated and wonder “what happens here again?” This activates our immune system and then that reaction occurs, which usually lasts about 24 hours.

More questions about the side effects of the vaccine

One of the most common effects after putting on the COVID-19 vaccine is the arm painThat is why the health workers always try to puncture the non-dominant arm, and this happens through the place where we give the injection. The prick is administered into the deltoides, a muscle that helps lift and lower the shoulder. The serum that is injected occupies a space and the muscle fibers in the area are sore, causing that sensation of pain.

Alcohol does influence the response of the immune system because it has an immunosuppressive effect and our immune system does not work the same if there is alcohol in the blood as if there is not.

The Spanish Medicines Agency notified last April that AstraZeneca’s COVID-19 vaccine produced 69 adverse effects per 100,000 inhabitants. Moderna’s, for its part, 332, becoming the one that has reported the most effects, and Pfizer’s 204 cases per 100,000 inhabitants.

Remember that with our tool AccountVaccines You can check the vaccination rate in your community and compare it with that of the rest of the territories.

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