where is the disease spread? Which treatment solutions?

CORONAVIRUSES. The researchers were able to culture the coronavirus and begin testing vaccines and possible treatments. Some doctors make attempts from cocktails of drugs used in other pathologies.

The essential

The 2019-nCoV coronavirus, born in a market in Wuhan in China, has killed 490 people and infected 20,600 people in more than twenty countries, according to the latest report. Abroad, two people died from coronavirus: a patient in the Philippines and another person in Hong Kong. Follow the live evolution of the coronavirus here
Researchers at the Institut Pasteur, as well as mainly Australian and Chinese scientists, are looking for a vaccine. After isolating and culturing the coronavirus, scientists are now testing various existing drugs on viruses. The development of a vaccine take more time, the Institut Pasteur estimates that it would be possible to validate a vaccine at the end of the summer of 2021. At the same time, in the field, doctors sometimes resort to cocktails of drugs usually dispensed for other pathologies, to treat patients with coronavirus.
In France, the six patients infected with the coronavirus are in a “stable” state, said the Director General of Health, Jérôme Salomon, this Monday evening. Only one of them is still in intensive care, in this case an 80-year-old Chinese man. Concerning the French repatriated from Wuhan and placed in quarantine in Carry-le-Rouet and Aix-en-Provence, the authorities declared that they were all fine. All the tests carried out are negative for the coronavirus.

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23:38 – France revises its definition of “possible cases” of the coronavirus

END OF LIVE – For the second time, French health authorities have widened their definition of “possible cases” of coronavirus this Tuesday, February 4. The aim is thus to better diagnose affected patients. 20 Minutes reports that, from now on, the “exhibition area” now extends to China, and no longer only to Hubei province. Possible cases are therefore now “any person with clinical signs of acute lower respiratory infection, whatever its severity, with a fever or a feeling of fever, and having traveled or stayed in China in the 14 days preceding the date of onset of clinical signs “.

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23:06 – Securities take off on the stock market “thanks” to the coronavirus

If the coronavirus has a negative impact on the economy, the situation is not bad for everyone. In fact, Les Échos reports that investors “are rushing to certain stocks linked directly or indirectly to the epidemic”. Among these values, we find in particular Zoom, “nugget of videoconferencing”, currently allowing people in quarantine to communicate with those around them. Or several giants of the vaccine: Inovio, Novavax … Without forgetting the manufacturers of masks, currently in short supply in several outlets.

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22:36 – The reassuring authorities after the case of coronavirus in Belgium

Among the passengers repatriated from Wuhan, one individual tested positive for the coronavirus in Belgium. The situation caused concern among people placed in quarantine in the south of France, since the patient was in the same plane. The authorities wanted to be reassuring and affirmed that among the 13 people who were potentially in contact, four have been tested negative and 3 others will be tested in the coming hours, reports 20 Minutes.

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22:21 – A petition to close American schools collects 14,000 signatures

Launched by an anonymous, a petition asking to close the schools near Los Angeles (district of Alhambra) collected more than 14,000 signatures. Given the number of infections, zero, the district responded that the schools were safe and that no closures were planned, as reported by 20 Minutes. Currently, only two cases of coronavirus have been identified throughout southern California (zero in the Alhambra). The petition mentioned the “suspected Alhambra case”.

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22:03 – Global tech threatened by coronavirus

The coronavirus epidemic, which has now affected more than 20,000 people in China, is impacting several sectors. And tech is no exception. In fact, as Les Echos reports, China remains an “essential” player, despite “the rise of certain countries in Southeast Asia”. However, the entire supply chain and sales are threatened due to contamination, causing tech companies to stop or almost stop.

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21:26 – French tour operators extend the suspension of trips to China

While organized trips to China were suspended until February 21, French tour operators pushed back the date until March 31 due to the coronavirus. This decision impacts around 3,000 French tourists, as indicated by 20 Minutes. Stays to other Asian countries are nonetheless maintained.

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20:50 – Coronavirus to delay US-China agreements

While massive purchases of American products were planned by China, 20 Minutes reports that the coronavirus is delaying the process. White House economic adviser Larry Kudlow admitted in an interview with Fox Business that it was “true that the trade agreement, the phase 1 trade agreement, and the explosion in exports (expected) of this trade agreement will take longer, because of the Chinese virus. ”

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20:07 – Plane turns around after bad joke

Some jokes went worse than others! This Tuesday, February 4, a plane that went to Jamaica turned around following the joke of a passenger claiming to have contracted the coronavirus, indicates 20 Minutes. The passenger had been fitted with gloves and a mask, and kept away from the rest of the passengers on the plane during the return journey. The aircraft was already halfway to its final destination. The man was arrested on arrival and will appear in court on March 9.

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19:29 – The French Ministry of Foreign Affairs changes its instructions

This Tuesday, February 4, a last minute publication by the Ministry of Foreign Affairs brought new general recommendations relating to the coronavirus. It says that “any trip to Wuhan and Hubei province is formally discouraged”, and “it is recommended to postpone any trip to China that is not essential”.

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18:50 – WHO director speaks on coronavirus

As the coronavirus epidemic continues to spread, the WHO director has accused rich countries of not sharing their information enough, as reported in Liberation. Tedros Adhanom Ghebreyesus said some countries were “far behind” in information, and added: “Of the 176 cases reported so far outside of China, WHO has received reporting forms. complete cases only 38% of the time. Some high-income countries are far behind in sharing this vital data with WHO. I don’t think it is due to lack of capacity. “

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6:24 pm – Beijing’s “shortcomings” in the coronavirus crisis

As cases of coronavirus contamination and death continue to increase in China, resulting in overcrowded hospitals and plummeting stock markets, local authorities have conceded to have been the cause of “shortfalls” and “difficulties in responding to the epidemic”.

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18:19 – No flight to China until the end of March via French tour operators

It is a decision which concerns nearly 3000 people in France: French tour operators are suspending organized trips to China, due to the coronavirus, until March 31. This concerns stays organized by Voyageurs du Monde, Kuoni, Costa Croisières, TUI France and all tour operator companies. Until then, the date of February 21 had been used as the end date of the suspensions.

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6:10 pm – British nationals asked to leave China

While three cases of coronavirus have been identified in the United Kingdom, London asks its nationals in China to leave the country, “if they can”. “We advise British nationals to leave the country if they can and to minimize their exposure to the virus,” said Foreign Minister Dominic Raab in a statement.

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The origin of the Chinese virus is still mysterious. The cradle of the coronavirus (2019-nCoV) is said to be the gigantic fish market in the city of Wuhan, in central China, where other animals pass through every week, in particular snakes or bats, suspected of being the first agents carrying the virus. If the animal origin of the virus no longer seems to make too much doubt, the fear of a mutation allowing human-to-human transmission is also legitimate, given the rapid spread of the epidemic. “The human-to-human transmission of 2019-nCoV is proven,” ruled Public Health France, the French public health reference center, on January 24.

The precise mode of transmission of the coronavirus is also still unknown. However, we know that viruses generally need a “host” to circulate. They are therefore transmitted almost systematically by the exchange of fluids, saliva, postilions, droplets from a sneeze or a cough. Public Health France adds contacts with “surfaces freshly contaminated by these secretions”. Transmission by physical contact or interposed objects is less likely, the infectivity of a virus decreasing very quickly outside a body.

The virus, contracted by several hundred Chinese since December, is one of the coronaviruses. This family of viruses encompasses several pathologies, whether in humans or animals, ranging from a simple cold to other more serious symptoms. In the case of this virus (2019-nCoV), the people affected were affected by significant respiratory disorders, high fever, symptoms similar to those observed during influenza or pneumonia. The Ministry of Solidarity and Health gives a fairly summary list of symptoms, simple signs of respiratory infection: “fever and cough / breathing difficulties”. For people with these symptoms who have stayed in China, you are asked to:

Contact Samu Center 15, reporting symptoms and recent stay in China.
Do not go to your doctor or to the emergency room, to avoid any potential contamination.

France is also one of the first European countries to have developed a test, thanks to the Institut Pasteur. This “quality” test “makes it possible to make a diagnosis in the space of a few hours”, according to Minister of Health Agnès Buzyn. Already available in Paris or Lyon, and “distributed in public hospitals in the course of next week”, it is this test which would have made it possible to detect the first patients in Europe.

There is no specific treatment or vaccine today against the human coronavirus. Only the symptoms of the disease are treated today. In other words, the only drugs prescribed to patients are drugs that fight pain and fever, but not the infection itself. In the event of serious breathing difficulties, more powerful treatments and respiratory aid can be administered, in France, in referral health establishments (ESR), hospitals designated and equipped to respond to exceptional health situations.

Several initiatives are multiplying, in China or in the United States, to develop a vaccine and treatments against the coronavirus, sometimes with massive means and the financial support of big companies like Alibaba or Apple. By analyzing the first French cases, the scientists at the Institut Pasteur managed to analyze its genetic code and promised a vaccine that would be operational in 20 months, that is, for the summer of 2021 if the virus does not mutate by then.

The announcement on Friday January 24 of the first confirmed cases of coronavirus (2019-nCoV) in France, Bordeaux and Paris, marked a new stage in the spread of the virus outside of China, and now on European soil. According to the authorities, six patients have been infected with the coronavirus and are in stable condition.

But beware, the risk of an epidemic emerging in France is currently ruled out. This virus is reminiscent of SARS, for severe acute respiratory syndrome, a coronavirus which has the distinction of having already struck China with devastating consequences between November 2002 and May 2003, the period in which more than 700 people had lost life (more on SARS here). Fewer than 10 people had been affected in France according to epidemiological data and no victims were then to be deplored. Even if the contagiousness and the mortality rate of the coronavirus can still evolve, it is estimated that it is for the moment a little less contagious than SARS, but also less deadly. A “moderate” contagiousness, the coronavirus displays a mortality rate of 2 to 3% against 9.6% for SARS, a rate which could go up to 43% in people over 60 years for this disease. The coronavirus would also be a little less contagious than the seasonal flu, which causes around 10,000 deaths each year in France, but on the other hand exceeds it in terms of mortality, the flu having a mortality rate of 0.3% .

On Thursday January 30, WHO officially declared an international health emergency regarding the coronavirus epidemic. In France, a daily information point is carried out every day by the Ministry of Health. Friday, January 31, the ministry set up a toll free number, 0800 130 000, open from 9h to 19h every day and reserved for “all questions that do not concern health”. The goal: to relieve 15 to answer questions “that are not medical” and that are not directly related to symptoms. “If people have symptoms and medical issues” and they return from China, always call centers 15, the ministry said.

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