Jakarta –
Understanding Oxycodone
Oxycodone is used to relieve pain that is severe enough to require opioid treatment and when other pain medications are not working well enough. Oxycodone belongs to a group of drugs called narcotic analgesics (pain relievers). Oxycodone works on the central nervous system (CNS) to relieve pain.
Oxycodone capsules or tablets should not be used if pain medication is needed for a short time, such as when recovering from surgery. Do not use this medication to relieve mild pain or in situations where non-narcotic medications are effective. This medication should not be used to treat pain that is felt only occasionally or ‘as needed’.
Oxycodone Dosage and Rules for Use
Intravenous
Moderate to severe pain
Mature
- Injection: 1-10 mg over 1-2 minutes, repeated no more than 4 hours.
- Infusion: Initially 2 mg/hour, increase as needed. Patient-controlled analgesia
- (PCA): 0.03 mg/kg, given with a lock-on time of at least 5 minutes.
- Elderly: Administer the lowest dose with careful titration to control pain.
Oral
Moderate to severe pain
- Adults: Initially, 5 mg every 4-6 hours may be increased as needed.
- Extended-release tablets: 5-10 mg every 12 hours. Maximum dose 400 mg/day.
Subcutaneous
Moderate to severe pain
Mature
- Injection: Initially, 5 mg every 4 hours.
- Infusion: Initially, 7.5 mg daily adjusted according to response.
- Elderly: Administer the lowest dose with careful titration to control pain.
Use oxycodone exactly as directed by your doctor or as directed on the label. Do not take more or less than directed by your doctor.
Patients can take oxycodone with or without food. Do not consume it with high fat foods. Try to take it at the same time every day.
If using extended-release or controlled-release tablets, swallow them whole. Do not break, chew, or crush the tablet.
Do not stop taking oxycodone unless instructed otherwise. Stopping it suddenly can worsen a person’s condition.
Forms of Oxycodone
- Tablets, extended-release tablets, capsules, syrups, solutions and injections.
Oxycodone group
- Opioid analgesic pain relievers
Kategori Oxycodone
Contraindications for Oxycodone
The use of this drug is contraindicated in patients with:
- Respiratory depression
- Bronchial asthma
- Hypercarbia
- Hypersensitivity to oxycodone
- Paralytic ileus
- Delayed gastric emptying (gastroparesis)
- Moderate to severe liver and kidney disorders
- Chronic Obstructive Pulmonary Disease (COPD)
- Respiratory depression, known or suspected paralytic ileus, acute abdomen, delayed gastric emptying, COPD, cor pulmonale, acute or chronic bronchial asthma, hypercarbia, chronic constipation. Concomitant administration of MAOIs or within 2 weeks of discontinuation of use. Moderate to severe liver and kidney disorders. Lactation.
Oxycodone Interactions
Opioid medications can interact with other medications and cause dangerous side effects or death. Make sure the doctor knows if the patient is also using:
- Other opioids (opioid pain medication or prescription cough medication)
- Sedatives include alprazolam, clonazepam, diazepam, lorazepam, temazepam
- Sleeping pills
- Muscle relaxants or sedatives
- Medication for depression, anxiety, or other mental illness
- Medicine for Parkinson’s disease
- Migraine headache treatment
- Medication used to prevent nausea and vomiting.
- Flu or allergy medicine, asthma medicine, or diuretic
- Medication for motion sickness, irritable bowel syndrome, or overactive bladder
Oxycodone Use Cautions
- This drug causes a serious allergic reaction called anaphylaxis which can be life-threatening. Call your doctor if you have a rash, itching, hoarseness, difficulty breathing or swallowing, swelling of the hands, face, or mouth.
- This medication may cause sleep-related breathing problems (e.g., sleep apnea, hypoxemia). Your doctor may lower your dose if you suffer from sleep apnea while using this medication.
- Dizziness, lightheadedness, or fainting may occur when suddenly getting up from a lying or sitting position. Getting up slowly can help reduce this problem.
- If you have been using this medication regularly for several weeks or more, do not change the dose or suddenly stop using it without consulting your doctor.
- Using this medication while pregnant may cause serious undesirable effects, including neonatal withdrawal syndrome in the newborn baby. Tell your doctor immediately if you are or plan to become pregnant while using this medication.
Side Effects of Oxycodone
Oxycodone may cause drowsiness and dizziness. This drug can cause people to suddenly fall asleep during daily activities such as eating and watching television even though they were not sleepy before. If affected, do not drive or participate in any activity that requires alertness.
- Other side effects include weakness, headache, rash, loss of appetite, nausea, vomiting, stomach ache, constipation, dry mouth, and sweating.
- Some side effects may require immediate medical attention. Tell your doctor quickly if you experience difficulty breathing, extreme drowsiness, changes in heart rate, and severe dizziness or confusion.
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2023-12-27 05:58:40
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