In someone with a hereditary predisposition to malignant hyperthermia (MH), the muscles may respond incorrectly to some medications. This concerns medications that can be used during surgery (anesthetic gases, muscle relaxants). Sometimes someone also gets such an MH attack when it is very hot or when someone is making a lot of effort.
The cause of the hereditary predisposition is a change in a gene.
During an MH attack, a person gets cramps in the skeletal muscles. The cells in those muscles can then break down in a short time and the body temperature becomes too high. Certain substances enter the blood from the damaged muscle cells. These substances can damage organs such as the kidneys and heart. A person may have a very fast heart rate and breathing very quickly during an attack. Someone can cardiac arrhythmias get and the blood pressure may be too low become.
Sometimes a person has only a few of these characteristics during an MH attack. The severity varies between individuals. Someone could die from it. But if proper treatment is given in time, a person can often get completely better. That is why it is important that someone knows that he or she has a hereditary predisposition to MH. Then perhaps an MH attack can be prevented.
There are diseases in which people are more likely to develop malignant hyperthermia (MH). For example central core myopathie (CCD) and Freeman-Sheldon syndrome.
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2024-01-30 14:37:50
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