As the WHO reports on its site, there is currently no drug approved for the treatment or prevention of Covid-19, but a large number of trials are underway to prevent or cure infection with the coronavirus. Overview.
and the vaccine approved to treat or protect against Covid-19, as recalled by government site and WHO. On the other hand, it has been several months since some scientists or some agencies recommend a particular drug to cure the coronavirus, without however benefiting from the Marketing Authorization (AMM). Treatments given to patients are currently only intended to relieve symptoms. For good reason, none of them has so far demonstrated undoubted efficacy against the disease. “Data-reactid =” 24 “> To date, there are still no drugs and the vaccine approved to treat or protect against Covid-19, as recalled by government site and WHO. On the other hand, it has been several months since some scientists or some agencies recommend a particular drug to cure the coronavirus, without however benefiting from the Marketing Authorization (AMM). Treatments given to patients are currently only intended to relieve symptoms. For good reason, none of them has so far demonstrated an indisputable effectiveness against the disease.
Covid-19, il n’en est finalement rien. Ces médicaments ont été deemed ineffective and are even suspected of adverse effects. “data-reactid =” 25 “> If there are still a few weeks drugs such as hydroxychloroquine and lopinavir / ritonavir treatment seemed to give encouraging signs to be effective drugs against Covid-19, it is ultimately not. These drugs have been deemed ineffective and are even suspected of side effects.
One drug that saves lives
dexamethasone, which would reduce mortality by a third in patients on mechanical ventilation and a fifth in those receiving oxygen, according to a large trial in Britain. “data-reactid =” 27 ” > Among the dozens of treatments that are currently being evaluated around the world, a few have already shown encouraging results. dexamethasone, which would reduce mortality by a third in patients placed on mechanical respiratory assistance and a fifth in those receiving oxygen, according to a large trial in Great Britain.
Used to treat chronic conditions such as rheumatoid arthritis or asthma for its strong anti-inflammatory effect, this steroid drug is inexpensive and there are many manufacturers of dexamethasone around the world.
called to increase global dexamethasone production. “data-reactid =” 30 “> On June 22, the WHO called to increase global dexamethasone production.
Another that reduces the length of hospitalization
remdesivir is also one of the drugs that have shown positive results. This drug manufactured by the American pharmaceutical company Gilead had been tested against the Ebola virus with little success, but can, according to several studies, both prevent and treat other coronaviruses such as SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East respiratory syndrome). “Data-reactid =” 32 “> The remdesivir is also one of the drugs that have shown positive results. This drug manufactured by the American pharmaceutical company Gilead had been tested against the Ebola virus with little success, but can, according to several studies, both prevent and treat other coronaviruses such as SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome).
the European Medicines Agency (EMA) recommended the authorization of a “conditional placing on the market” of this antiviral within the EU, before the European Commissionauthorizes its marketing on July 3. This is also a drug reserved for patients with a severe form of the disease. “Data-reactid =” 33 “> At the end of June, the European Medicines Agency (EMA) recommended the authorization of a “conditional placing on the market” of this antiviral within the EU, before the European Commissionauthorizes its marketing on July 3. This is also a medicine reserved for patients with a severe form of the disease.
Professor Raoult, known to defend hydroxychloroquine, attacked the molecule of the American laboratory Gilead on his Twitter account. “data-reactid =” 34 “> For his part, Professor Raoult, known to defend hydroxychloroquine, attacked the molecule of the American laboratory Gilead on his Twitter account.
Remdesivir is not a cure. Worse, it causes kidney failure: in the first 5 patients treated with this drug at Bichat hospital @APHP, 2 were put on dialysis.
When will we have the results of Discovery?
What is the WHO waiting for to react? https://t.co/Z92kZ3AdZJ– Didier Raoult (@raoult_didier) July 9, 2020
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“Huge potential” for an inhalation drug
it would reduce the risk of developing a severe form of Covid-19 by 79%. Developed by the British pharmaceutical company Synairgen, this inhaled treatment uses beta interferons, a natural protein that is involved in the body’s response to viruses. “Data-reactid =” 37 “> According to a study conducted by the University of Southampton (Great Britain), nebulized treatment reduces the number of hospitalized patients requiring intensive care. Called SNG001, it would reduce the risk of developing a severe form of Covid-19 by 79%. Developed by the British pharmaceutical company Synairgen, this inhaled treatment uses beta interferons, a natural protein that is involved in the body’s response against viruses.
If the study was carried out on a small sample of patients, Synairgen Managing Director Richard Marsden said it could be a “major breakthrough” in the way the disease is treated. Tom Wilkinson, chief investigator of the trial, evokes “enormous potential as an inhaled drug to be able to restore the immune response of the lungs, strengthen protection, accelerate recovery and counter the impact”.
Steve Goodacre, professor of emergency medicine at the University of Sheffield, believes for his part that the results are for the moment “not interpretable” because of a “lack of complete details of the protocol of the trial”.
1/ Thread SNG001
Some nuances, if we look closely:
400 participants planned on clinical trials, and results on 100 hospi (120 non-hospi in progress).severe form protection (OR 0.21 [95% CI 0.04-0.97]; p=0.046). https://t.co/VW2CaTGABt
— MARY Aurélien (@MARYau_MCU_PH) July 20, 2020
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1751 tests in progress
France) en tout sont à l’étude dans le monde sur plusieurs dizaines de traitements, selon the basis of the Lancet. “data-reactid =” 46 “> Apart from these three drugs mentioned which are to date the drugs which have shown the most encouraging signs (even if some still express a lot of reservations about SNG001), many other treatments are there. ‘object of evaluations. 1751 clinical trials (including 120 in France) in all are being studied in the world on several tens of treatments, according to the basis of the Lancet.
