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Research into the usefulness of a second shot after the first Janssen vaccine | Inland

Four academic hospitals will investigate whether it is useful to give people who have been vaccinated with Janssen’s corona vaccine a second shot. In principle, one shot is sufficient for this vaccine, certainly to prevent serious illness from the virus. “Due to the increasing circulation of certain variants of the coronavirus, it is possible that an additional vaccination is necessary after one shot of Janssen,” reports Erasmus MC.




The hospital in Rotterdam will investigate the effects of a second dose, together with Amsterdam UMC, Leiden UMC and UMC Groningen. The test subjects who receive a second injection are employees of the four centers. Some of them receive the Janssen vaccine again as a second shot. Others receive a dose of the corona vaccines from Pfizer/BioNTech or Moderna.

Mixing vaccines can have a number of potential benefits. Efficacy against the coronavirus is paramount, but if one person can get two shots from different manufacturers, vaccination campaigns become more flexible. The vaccination process can then be faster and the impact of delivery problems is less.

The first foreign studies into combining an AstraZeneca vaccine with another vaccine indicate that this is safe and produces a good immune response.

The first results are expected at the end of October. The Health Council is also still working on an advice on combining corona vaccines.

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