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Goodbye hangovers: Australian scientists create a vaccine against excess alcohol

Scientists in Australia have developed an experimental vaccine called “Sober Up” that could reduce the side effects of alcohol consumption on the body, including the dreaded hangover. The vaccine, administered before drinking, aims to inhibit an enzyme in the liver that breaks down alcohol into a toxic byproduct that causes malaise, headache and nausea.

According to the study, published in the research journal Cell Metabolism, the potential of the hormone FGF21 (fibroblast growth factor 21), which is normally found in the liver, to target the liver-brain pathway and treat acute alcohol poisoning. As part of the experiments, large doses of FGF21 have been shown to speed up the sobriety process, not by reducing alcohol levels in the body, but by stimulating brain cells.

Scientists have concluded that the liver not only works on itself, in its usual functions, but also communicates with other organs and can help mitigate the prolonged effects of alcohol, since it has the potential to send signals to the brain to protect it. .

While the initial study in mice has shown promising results with a 50% reduction in levels of a key liver enzyme, human clinical trials are still needed to determine the vaccine’s effectiveness and safety. The researchers are seeking funding to conduct these clinical trials.

Although the idea of ​​a hangover vaccine may seem appealing to many, some health experts have warned that it could encourage excessive drinking if people believe they can avoid negative side effects. In addition, a hangover is a signal that the body sends us to moderate our alcohol consumption in the future.

However, if the vaccine is used in combination with responsible alcohol consumption, it could have the potential to reduce the negative impact of alcoholic beverages on health and well-being.

At the moment, the “Sober Up” vaccine remains experimental and more research is needed before it can be considered as a viable option for the general public.

Although the “Sober Up” vaccine has the potential to reduce the negative effects of alcohol on the body, it is important to remember that responsible consumption is still the best option for our health. The vaccine is an interesting option that can have a positive impact on society if it is used appropriately and responsibly.

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