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Doctors adopt Trump-promoted medicine without solid evidence that it works against covid-19

A drug with decades of history, that the president Donald trump has consistently promoted as a possible weapon against the covid-19, has become in weeks a standard of care in areas of U.S affected by pandemicBut doctors who prescribe it have no idea if it works.

The medical Y pharmacists of more than half a dozen major health care systems in NY, Louisiana, Massachusetts, Ohio, Washington Y California they said they habitually use hydroxychloroquine in hospitalized patients with covid-19.

However, several said they have seen no evidence that the drug, used for years to treat malaria and disorders autoimmune, have any effect on the virus.

File image of President Donald Trump, during a press conference with the workforce to contain the spread of the coronavirus, at the White House, Washington, USA, on April 5, 2020.


The use of hydroxychloroquine has been triggered after U.S quickly became the epicenter of the pandemic. More than 355,000 people in the country have tested positive for the new coronavirus and more than 10,000 have dead.

Faced with the numbers and in the absence of known effective treatments, medical frontline they said they started using hydroxychloroquine and the chloroquine related in patients who are deteriorating, because some small studies suggest a possible benefit.

Some said they had been pressured by patients to use the therapies widely promoted by Trump and some of his supporters.

“I could take it,” he said Trump on Saturday, referring to the hydroxychloroquine, although it has been negative twice for the coronavirus, according to White House. “We only hear really positive things and continue to collect the data.”

Possible side effects of hydroxychloroquine include loss of vision and problems cardiac.

However, doctors said they were comfortable prescribing the drug for a short time for patients with coronavirusbecause the risks are relatively low and the therapies are economic and they are generally available.

However, protocols that indicate how these should be used drugs They vary from hospital to hospital, including when to prescribe them and whether to combine them with other medications.

In addition, some studies with promising results involved patients who used therapy for mild or early-stage disease, so many of those people are likely to have recovered on their own.

Patients admitted to hospitals in U.S they are generally much sicker than the mild cases cited in the studies. According to doctors, these factors have made it difficult for them to determine if medications are making a difference.

“I have seen hundreds of patients with covid-19 serious and most of these people take hydroxychloroquine“the doctor said in an email Mangala Narasimhan, regional director of critical care for Northwell Health, a system of 23 hospitals in NY.

“In my opinion, although it’s very early, I don’t see a dramatic improvement in hydroxychloroquine in these patients. “

He Doctor Daniel McQuillen, specialist in infectious diseases at Lahey Hospital and Medical Center in Burlington, Massachusettssaid that so far he has prescribed a course in hydroxychloroquine for about 30 patients with covid-19 because the medicine has shown “a little activity antiviralBut he has not seen “marked improvement in patients.”

Anecdotallymay have had limited effect in patients with milder disease, “he said McQuillen. The therapy “has had no effect in limiting or slowing the progression of our patients who were at or near the ICU level when they arrived.”

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