A major cause of Alzheimer’s is the buildup of beta-amyloid protein in the brain, where it forms plaques. Scientists from the University of Hokkaido and Toppan have succeeded in developing a technology capable of detecting this accumulation. Their blood test actually detects certain biomarkers (beta-amyloid-binding exosomes), which increase as beta-amyloid proteins build up in the brain. An advance that for the moment has proved… on the mouse.
“Other than the lack of effective treatments for Alzheimer’s, there are few methods of diagnosing it,” the authors note. “This pathology can only be definitively diagnosed by direct brain examination through an autopsy. Accumulation of beta-amyloid in the brain can be measured by cerebrospinal fluid tests or positron emission tomography. However, the first test is extremely invasive and the second is quite expensive. Therefore, a diagnostic test is needed that is both inexpensive, accurate and widely available. “
Furthermore, an early diagnosis would make it possible to set up a treatment, medicinal or not (cognitive stimulation, psychological treatment, speech therapy, etc.) as soon as possible.
Alzheimer’s disease: why are women twice as affected?
