Medical personnel take a sample from a person’s nose at a coronavirus test station. Image: dpa / Ted S. Warren
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Coronavirus probably enters the body primarily through the nose
We know that the coronavirus spreads mainly through droplet infection and enters the body through certain proteins. Researchers now wanted to know which cells contain these proteins – and where they are located.
Special cells in the nose are according to a study
the most likely entry points for the new corona virus.
Several research teams had cells from the lungs, nose, eyes, intestines,
Heart, kidney and liver are examined like the Max Delbrück Center for
Molecular Medicine (MDC) in Berlin reported on Thursday.
she
wanted to find out which cells are the two most important
Entry proteins ACE2 and TMPRSS2 contain the virus for the
Infection. “We then showed that of all the cells
mucus-producing goblet cells and cilia in the nose
have the highest concentrations of these two proteins, “explained
Lead author Waradon Sungnak from the Wellcome Sanger Institute. “That makes
these cells become the most likely primary route of infection for the virus. ”
Other possible routes of infection
The two most important entry proteins are also in
To find corneal cells of the eye and in the intestinal mucosa
the Max Delbrück Center continued to report. That points to one
another possible route of infection via the eye or the
Tear glands.
So there is also potential for one
Transmission via faeces and ingestion by mouth, writes
rather cautious of the MDC. The research teams have their result in
Technical journal “Nature Medicine” published.
Various institutes were involved in the study, including some
the Wellcome Sanger Institute, the University Hospital Groningen and
the University of Cote d’Azur and the Human Cell Atlas Lung
Biological Network.
According to the, up to 20 percent of corona patients suffer
MDC message damage to the heart muscle up to heart failure. Also
the docking station for the corona virus was found there. Not clear
however, is still whether the virus itself causes the damage to the heart
or whether it’s secondary effects.
(pcl / dpa)
