10:00 AM
Saturday 02 May 2020
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I wrote- Amira Helmy
Dr. Alaa Hashish, Infectious Diseases Officer at the WHO office in Egypt, revealed, in an interview with “Masrawy”, that a number of REMDIVESIVER packages are available in Egypt soon, to start using it in the clinical trials of (Covid 19) caused by a virus. Corona Novelty.
The US Food and Drug Administration plans to announce the issuance of its emergency approval for the use of the drug “Remdisever”, for the purpose of treatment, after the results of his experience showed his success in shortening the recovery time.
Remdesivir presented a ray of hope in the fight against the Corona virus this week, when the results of a promising clinical trial were released, after the experiment revealed that it could speed up recovery in some patients. The American immunologist, Dr. Anthony Fossey, described it as a “step A very important first “in treating the virus, and he said that the US Food and Drug Administration would likely agree to use the drug against the virus” very quickly “.
Gilead Sciences pledged to “provide adequate supplies to patients worldwide.”
What is Ramesdiver and why was it developed?
It is an experimental antiviral drug that was first developed by American drug company Gilead Sciences to treat Ebola.
The drug, developed in 2015, showed early promises in an animal study and was later released in the Democratic Republic of the Congo – but ultimately failed as an effective treatment for Ebola, according to Russia Today.,
Speaking to the New York Post, Peter Bates, a former assistant commissioner of the Food and Drug Administration, said: “He never showed promising; relatively unsuccessful against Ebola. So, doctors said let’s see if he works against Coffid-19.”
How effective is it against the Corona Virus?
The results of a clinical trial, conducted on more than a thousand people, showed that Covid-19 patients with respiratory problems improved by 31% faster than those who took the placebo, according to the National Institute of Allergy and Infectious Diseases.
But Bates cautioned that the drug showed benefit only in patients, who were hospitalized elderly, and who had respiratory or previous health problems. “It saves lives but it does not change the rules of the game. Clinical trials have shown that it has led to recovery in 4-10% of patients with severe disease,” he said.
How does remisevir work?
To get the job done, the drug mimics adenosine, one of the four building blocks of viral RNA – also known as RNA, and when a virus merges a remedivifer in its genome instead of adenosine, it becomes unable to reproduce, according to AFP.
“It enters itself into the viral RNA, and causes the virus to terminate prematurely,” Bates said.
– What are the side effects of Remsdevir?
According to the results of the most recent study published by Gilead Sciences, the most common adverse reactions were nausea and acute respiratory failure. About 7% of patients experienced a rise in liver enzymes.
– How much will Remisdiver cost?
This is still unclear, although Daniel Oday, CEO of Gilead Sciences, told Stat News this week that the company is donating 1.5 million doses of the drug – about 140,000 courses of treatment – to hospitals, and has pledged “to work with the government and with systems Health care, to ensure access to medicine, and to make it accessible to governments in the future. ”
How should we be excited about the remedifier?
It’s just a drug, not a miracle cure, and doctors say they need to know more about it. Some experts consider it “a good guide” that could pave the way for better treatments.
“Clinical trials have shown a very positive effect on those who were hospitalized. But for the time being, it’s still an experimental drug,” Bates said.
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