Correction Issued to Landmark Study on Dementia Risk Factors
A correction has been published regarding research into the complex interplay of genetics, metabolic markers, and diet in the growth of dementia and its impact on cognitive function. The updated article, authored by Yuxi Liu and colleagues, appears in the journal Nature Aging on October 2, 2025.
The original study, and now the corrected version, investigates how genetic predispositions combine with specific metabolites found in the blood – the ”plasma metabolome” – and adherence to a Mediterranean diet to influence an individual’s risk of dementia and their overall cognitive performance. This research is critical as dementia rates continue to rise globally, placing increasing strain on healthcare systems and families. Understanding these combined risk and protective factors is essential for developing targeted preventative strategies and potential interventions. The correction ensures the accuracy and reliability of the data, furthering the scientific community’s ability to address this growing public health challenge.
The research team analyzed data from a large cohort to identify specific genetic variants and metabolic profiles associated with dementia risk. Their findings suggest that individuals with certain genetic predispositions may be more vulnerable to the negative effects of unfavorable metabolic profiles, but that a Mediterranean diet can perhaps mitigate these risks. The correction addresses details within the original publication to ensure clarity and precision of the reported results.
Further data regarding reprints and permissions for this article can be found through Springer Nature’s copyright center (contentID: 10.1038/s41591-025-04025-7). This work is a U.S. Government work and is not under copyright protection within the United States, though foreign copyright protections may apply. The article is openly accessible under a Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), allowing for broad use, sharing, and adaptation with appropriate attribution.
