Home » Technology » Assessment of dry-fogged hydrogen peroxide as an “untact” room disinfection automation system for rapid terminal decontamination of a single isolation room in a healthcare institution | Antimicrobial Resistance & Infection Control

Assessment of dry-fogged hydrogen peroxide as an “untact” room disinfection automation system for rapid terminal decontamination of a single isolation room in a healthcare institution | Antimicrobial Resistance & Infection Control

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Automated “Untact” Room Disinfection system Utilizing Dry-Fogged Hydrogen Peroxide

the operation of the “untact” room disinfection automation system, employing dry-fogged hydrogen peroxide (dHP), is designed for enhanced safety and efficiency.Upon initiation, all room access points are automatically secured by safety locks, preventing entry during the disinfection cycle. Once the disinfection process is successfully completed, the operator can confirm the absence of hydrogen peroxide by observing a 0 ppm reading on the human interface monitor. Activating the termination button disengages the safety locks,thereby restoring normal room accessibility.

Fig. 2 illustrates the operational workflow of this automated disinfection system. the room-temperature disinfection procedure using hydrogen peroxide unfolds in three distinct phases. initially,during the fogging and injection phase,the hydrogen peroxide solution is transformed into a fine dry-fog,with droplet sizes less than 10 micrometers. This fog is then dispersed to thoroughly saturate all surfaces within the designated room. Afterward, in the dwelling phase, the dHP is allowed to settle, forming micro-condensations on both surfaces and within the air. the reactive oxygen species generated from the decomposition of hydrogen peroxide then engage with microorganisms, disrupting their cellular structures and effectively eliminating them. The final stage is the aeration phase, during which any remaining hydrogen peroxide is swiftly removed from the disinfected habitat. This removal is facilitated by a catalytic filter and a high-efficiency particulate air (HEPA) filter, both integrated with the hospital’s existing heating, ventilation, and air conditioning (HVAC) system. While the primary disinfection process is automated,it is crucial to note that manual cleaning remains a necessary step to address any surface stains caused by organic matter contamination.

In our experimental setup,the fogging and injection phase lasted for 6 minutes,followed by a 20-minute dwelling phase,and concluded with a 100-minute aeration phase. To ensure optimal and uniform dispersion of the dHP throughout the room, the disinfection device was strategically positioned at a 45-degree angle relative to the room’s entrance.

Statistical Analysis

To evaluate the effectiveness of the URDAS application using dHP, the proportion of sites from which pathogens were successfully recovered before and after the treatment was compared using Fisher’s exact test. Furthermore, the total number of pathogen-positive samples collected from single isolation rooms prior to and following the dHP-based URDAS application was analyzed using the Yates’ corrected chi-square test.All statistical analyses were conducted using SPSS software, specifically version 23.0 (SPSS Inc., Chicago, IL, USA). A importance level of P < 0.05, resolute by two-sided testing, was considered statistically significant.

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