Melatonin Use Linked to Increased Heart Risks in New Study, Raising Concerns Over Long-Term Supplementation
Rome, Italy – Long-term use of melatonin, a popular over-the-counter sleep aid, might potentially be associated with increased rates of heart failure, related hospitalizations, and all-cause mortality, according to preliminary research extracted from a large international database of medical records. The study, currently not yet peer-reviewed, compared individuals with chronic insomnia who had consistently taken melatonin for at least one year with a similar group who had never used the supplement. Over a five-year follow-up period, the melatonin group exhibited higher instances of adverse cardiovascular events.
Researchers caution that melatonin supplements “may not be so harmless” as previously believed, and confirmation of these findings could significantly alter medical recommendations regarding sleep remedies. however, the study authors emphasize limitations, noting the analysis is preliminary and cannot definitively exclude the possibility that underlying insomnia or other pre-existing conditions contributing to melatonin use are responsible for the observed cardiac risks.
The findings underscore the importance of avoiding prolonged self-treatment with melatonin.Experts advise using the supplement only as a temporary and targeted intervention,after addressing treatable causes of insomnia and implementing good sleep hygiene practices – including consistent sleep schedules,limiting screen time before bed,and moderating caffeine,alcohol,and evening meals. Individuals with pre-existing heart conditions, high blood pressure, diabetes, or other cardiovascular risk factors are strongly urged to consult with a physician before initiating or continuing melatonin supplementation.
A particular concern highlighted by the research centers on the United States market, where many over-the-counter melatonin products lack rigorous quality control and purity standards, leading to potential dosage inconsistencies between brands.
The study suggests melatonin remains a potentially useful tool when used appropriately and for limited durations, but challenges the notion of it as a harmless, long-term “sleep vitamin.” Those currently taking melatonin for extended periods are advised to consult a healthcare specialist.
